thioester

(redirected from Thioesters)

thi·o·es·ter

(thī'ō-es'tĕr),
In enzymology, an ester where the oxygen bridging the substrate or product carbonyl carbon and the enzyme is replaced by a sulfur (usually through a Cys residue); a high-energy intermediate in many enzymes.
Synonym(s): acylmercaptan

thioester

/thio·es·ter/ (-es´ter) a carboxylic acid and a thiol group in ester linkage, e.g., acetyl coenzyme A.

thioester

[thī′ō·es′tər]
an important group of biological chemicals formed by the hydrosulfides (or mercaptans or thiols) and carboxylic acids and identified by a bond between the acyl carbonyl carbon and the thiol sulfur. Examples include the coenzyme A thioesters.
References in periodicals archive ?
T1AM upregulate members of the PAR (Proline and Acidic amino acid Rich), a subfamily of transcription factors involved in the circadian transcription of genes encoding acyl-CoA thioesterases, leading to a cyclic release of fatty acids from thioesters.
In addition, the genotoxicities of bone marrow and mammary tumors in mice caused by benzo(a)pyrene and 7,12-dimethylbenzo(a)anthracene, respectively, were reduced after treatment with diallyl thioesters, selenium-enriched garlic, and black tea [38-41].
Herein, we report the first synthesis of thioesters 2 and amino acid esters 3 from the reaction of some pyrazole-3- carboxylic acid chloride 1 with thiol and amino acid derivatives.
Subsequent addition of a nucleophile (or a diene) would results in highly valued and polyfunctional non-racemic carboxylic acids, amides and thioesters with water as the stoichiometric waste.
583 Hepatic lipase Hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters -0.
The gel is cross-linked through branched thioesters.
At K 2013, the company said it will maintain and develop established product lines like Anox[R] and Lowinox[R] phenolic antioxidants, Alkanox[R] and Ultranox[R] phosphite antioxidants, and Naugard[R] thioesters and amines.
Substrate specificity was similarly determined by assay against three thioesters (Weber, 1966).
alpha]-Methylacyl coenzyme A racemase (AMACR) is an enzyme that catalyzes the racemization of [alpha]-methyl-branched carboxylic coenzyme A thioesters.
A new study led by University of Kentucky researchers showed that the phi29 DNA packaging nanomotor connector could be used to sense chemicals with reactive thioesters or maleimide using single channel conduction assays based on three observable fingerprints.
Chemtura's customers benefit from its proprietary, Non Dust Blend (ANOX NDB stabilizer blend) technology, which allows thioesters to be synergistically blended with other additives and extruded into compact pellets using a patented process.