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In enzymology, an ester where the oxygen bridging the substrate or product carbonyl carbon and the enzyme is replaced by a sulfur (usually through a Cys residue); a high-energy intermediate in many enzymes.
Synonym(s): acylmercaptan
References in periodicals archive ?
Besides, LIPC gene is a critical enzyme in HDL metabolism which has the function of encoding hepatic triglyceride lipase and catalyzing the hydrolysis of phospholipids, monoglycerides, diglycerides, triglycerides, and acylCoA thioesters [45,46].
This enzyme utilizes thioesters of hydroxyalkanoic acids as substrate and converts them into polyhydroxyalkanoic acids [31].
The secondary antioxidants include sulfur and phosphorous compounds such as sulphides, thioesters, disulphides, and phosphates.
T1AM upregulate members of the PAR (Proline and Acidic amino acid Rich), a subfamily of transcription factors involved in the circadian transcription of genes encoding acyl-CoA thioesterases, leading to a cyclic release of fatty acids from thioesters. Produced fatty acids then act as ligands for PPAR[alpha] (Peroxisome Proliferator-Activated Receptors [alpha]), and activate transcription of genes encoding proteins involved in the uptake and cholesterol metabolism (Gachon et al., 2011).
In addition, the genotoxicities of bone marrow and mammary tumors in mice caused by benzo(a)pyrene and 7,12-dimethylbenzo(a)anthracene, respectively, were reduced after treatment with diallyl thioesters, selenium-enriched garlic, and black tea [38-41].
Keywords: Furan-2,3-dione; Pyrazole-3-carboxylic acid; Thioesters; Oxazole; Amino acid ester.
Subsequent addition of a nucleophile (or a diene) would results in highly valued and polyfunctional non-racemic carboxylic acids, amides and thioesters with water as the stoichiometric waste.
The gel is cross-linked through branched thioesters.
The O-esters hydrolyzed already in 2 M sodium hydroxide at 30-40[degrees]C overnight, whereas S-alkyl thioesters required 5M concentration, and O,O-dialkyl N,N-dialkylphosphoroamidates did no undergo hydrolysis in the above conditions.
During hydrolysis, free SH-group is released from the thioesters of choline which hydrolyzed the dye DTNB to form the yellow product.
Enoyl-CoA hydratase Straight-chain enoyl-CoA thioesters from C4 up to at least C16 Alpha-internexin Class-IV neuronal intermediate filament Fatty acid-binding High specificity for fatty acids.
At K 2013, the company said it will maintain and develop established product lines like Anox[R] and Lowinox[R] phenolic antioxidants, Alkanox[R] and Ultranox[R] phosphite antioxidants, and Naugard[R] thioesters and amines.