therapeutic range


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Related to therapeutic range: minimum effective concentration

ther·a·peu·tic range

refers to either the dosage range or blood plasma or serum concentration usually expected to achieve desired therapeutic effects. Some patients require doses (or concentrations) above or below this range. Some patients will experience drug toxicity within this range.

therapeutic range

Therapeutics The range of concentrations at which a drug or other therapeutic agent is effective with minimal toxicity to most Pts. See Clearance.

ther·a·peu·tic range

(thār'ă-pyū'tik rānj)
Either the dosage range or the blood plasma or serum concentration expected to achieve therapeutic effects.
References in periodicals archive ?
Aims: To evaluate the time in therapeutic range percentages, efficacy, safety and awareness of warfarin according to the different geographical regions in patients who participated in the WARFARIN-TR study (The Awareness, Efficacy, Safety and Time in Therapeutic Range of Warfarin in the Turkish population) in Turkey.
An adult therapeutic range for the anti-Xa assay is 0.
The 56% of patients in the therapeutic range had a mean SLEDAI of 2.
10) In greyhounds, pharmacokinetic studies of oral and intravenous amitriptyline show extremely poor oral bioavailability (6%), suggesting that the current recommended oral dose does not reach the human plasma therapeutic range of 60-220 ng/mL.
You do a disservice to patients with new-onset atrial fibrillation by using warfarin, because some patients will get into the therapeutic range but others never will.
In this case lithium intoxication occurred at a much lower blood concentration, at the lower end of the therapeutic range.
Two consecutive INR values should be in the therapeutic range during the overlap.
But these were at a lower level than the therapeutic range," the doctor said.
1) Because of the potential clinical risks for a narrow therapeutic range and significant biological variation, UFH therapy must be monitored.
However, it was difficult to regulate blood levels of fampridine, which has a narrow therapeutic range, and the sustained formulation, dalfampridine, was developed to overcome this limitation.
Furthermore, in some cases the therapeutic range, which indicates concentration values for which the substance is pharmacologically useful, is close to the toxic dose, in which there are complications in the context of the patient's health that can lead to intoxication and later to death.
5 before reaching the therapeutic range after further changes were made to her dosage.

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