Gal-1 was intensely expressed in the ovarian stroma, including the interstitial glands and
theca interna, and in the corpus luteum.
(39-42) Histologic examination revealed that the vascular density in the
theca interna of follicles in VEGF-treated ovaries increased two-fold compared with that in untreated ovaries.
In conclusion, our study showed that miRNAs have played an important role in insulin action in local ovarian
theca interna. And the downregulation of miR-92a and miR-92b might lead to augmentation of signal transduction in both androgen pathway and insulin pathway.
Microscopic examination reveals well-circumscribed nodules of steroid hormone-producing cells, intermediate in size between luteinized granulosa cells and luteinized
theca interna cells.
This capsule consists of two concentric layers of cells: an outer theca externa and an inner
theca interna. The inner layer is supplied with capillaries and contains endocrine cells.
It has been suggested that hyperinsulinemia and luteinizing hormone together could induce the changes that lead to polycystic ovary morphology, such as ovarian stroma and
theca interna hyperplasia, and could contribute to menstrual dysfunction in adolescent girls, she said.
Microscopic appearance shows a cyst lined by inner granulose cell layer and outer
theca interna cell layer.
The influence of the hormonal status of swine related to the stage of the oestrous cycle on adiponectin expression in corpora lutea, granulosa, and
theca interna cells remains unknown.
Moreover, nicotine has been shown to inhibit the induction of progesterone synthesis in cumulus cells by FSH and the production of other androgens by
theca interna cells (14).
The thecal cells form two distinct layers: a richly vascularized inner layer of endocrine cells (
theca interna) separated from a connective tissue layer (theca externa) by a fibrous capsule.
Characterization of dissimilar steroid productions by granulosa,
theca interna and theca externa cells during follicular maturation in the turkey (Meleagris gallopavo).
(7,8) In addition, part of the renal tubule, spermatogonia and Leydig cells of the testis, ova, theca externa, and
theca interna of the corpus luteum of ovary also expressed PGP9.5.