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channel

 [chan´el]
a passage, cut, or groove through which something can pass or flow across a solid structure.
calcium channel (calcium-sodium channel) a slow voltage-gated channel very permeable to calcium ions and slightly permeable to sodium ions, existing in three subtypes designated L, M, and N and located throughout the body; calcium channels are the main cause of action potentials in certain smooth muscles, and the N channels regulate neurotransmitter release.
fast channel a protein channel, such as a sodium channel, that becomes activated relatively quickly; a fast voltage-gated channel has a much lower activation potential than does the slow type. See also slow channel.
ligand-gated channel a protein channel that opens in response to the binding of a molecule (the ligand) to the protein, which causes a conformational change in the protein molecule. See also voltage-gated channel.
potassium channel a slow voltage-gated channel selective for the passage of potassium ions, found on the surface of a wide variety of cells, including nerve, muscle, and secretory cells; its functions include regulation of cell membrane excitability, regulation of repetitive low frequency firing in some neurons, and recovery of the nerve fiber membrane at the end of the action potential.
protein channel a watery pathway through the interstices of a protein molecule by which ions and small molecules can cross a membrane into or out of a cell by diffusion; protein channels play a vital role in depolarization and repolarization of nerve and muscle fibers, and may have physical characteristics such as shape or diameter that particularly attract certain ions.
slow channel a protein channel such as the calcium channel that is slow to become activated; a slow voltage-gated channel has a much higher activation potential than does the fast type. See also fast channel.
sodium channel a type of fast channel selective for the passage of sodium ions. Voltage-gated sodium channels are the main causes of depolarization and repolarization of nerve membranes during the action potential. In cardiac cells they produce phase 0 of the action potential.
voltage-gated channel a protein channel that can be opened or closed in response to changes in the electric potential across a cell membrane. See also ligand-gated channel.
water channel a channel in a cell membrane that permits passage of water molecules; chemical substances such as vasopressin cause the opening of new channels and increase permeability.

chan·nel

(chan'ĕl),
A furrow, gutter, or groovelike passageway.
See also: canal.
[L. canalis]

channel

/chan·nel/ (chan´ĕl) that through which anything flows; a cut or groove.
gated channel  a protein channel that opens and closes in response to signals, such as binding of a ligand (ligand-gated c.) or changes in the electric potential across the cell membrane (voltage-gated c.) .
potassium channel  a voltage-gated protein channel selective for the passage of potassium ions.
protein channel  a watery pathway through the interstices of a protein molecule by which ions and small molecules can cross a membrane into or out of a cell by diffusion.
sodium channel  a voltage-gated protein channel selective for the passage of sodium ions.

channel

(chăn′əl)
n.
1. A furrow, tube, or other groovelike passageway through which something flows.
2. An aqueous pathway through a protein molecule in a cell membrane that modulates the electrical potential across the membrane by controlling the passage of small inorganic ions into and out of the cell.

channel

Etymology: L, canalis, pipe
1 a passageway or groove that conveys fluid, such as the central channels that connect the arterioles with the venules.
2 membrane-bound globular proteins that allow diffusion of specific ions and molecules across a cell membrane.
enlarge picture
Membrane channel
Drug slang A regional street term for a vein into which a drug is injected
Paranormal See Channeler, Energy channel
Physiology A multiprotein transmembrane complex—ionophore—with an amphipathic pore, which is hydrophobic on either side of the membrane and hydrophilic inside

channel 

A concept relating to the evidence that information about a particular feature of an image is transmitted and processed in the visual pathway approximately independently of information about other domains. The evidence was obtained from various experiments: matching, threshold elevation, after-effect, etc. Examples: the three channels of colour vision theory; the spatial frequency channels. See waterfall after-effect.

chan·nel

(chan'ĕl)
A furrow, gutter, or groovelike passageway.
[L. canalis]

channel,

n a definite furrow, groove, or tubelike passage.
channel, vascular,
n a blood or lymph vessel through which inflammatory infiltrate and periodontitis proceed from a localized superficial area to involve the deeper structures of the periodontium.

channel

in biophysical terms these are the 'pores' in semipermeable membranes through which specific physicochemical units, e.g. cations, calcium ions, can pass; the rate of passage of some channels may be much slower than others, hence there is an expansive nomenclature, e.g. slow calcium channel, fast calcium channel.
References in periodicals archive ?
The images of the KcsA channel "explained beautifully why sodium can't go through the channel," says Bruce Bean of Harvard Medical School in Boston.
Unlike most inorganic heavy metals, methylmercury is lipophilic and may permeate cells directly through the phospholipid bilayer or as a cysteine complex and exert intracellular effects in addition to blocking the channel pore.
Wellstone made a brief appearance at the Channel One hearing to say that educators in his state like using the program, but as a teacher, he thought current events could be taught without it.
The depth of the channel in the early single loop inductors was in the range of 2 in.
Therefore, to effectively communicate, managers must be alert to the dynamic interplay of the message and the channel.
Retired legend Billie Jean King, who is a member of the channel's advisory board, said fans will be ``ravenous'' to get the channel.
We're extremely proud to introduce a service that helps create a community within the channel.
The Channel Gateway 3200 is Luminex's FICON-based secure distribution product that enables mainframe tape data to be transparently encrypted and distributed on CD or DVD media to non-mainframe environments.
The CRN Channel Chiefs are an elite group of individuals that consistently ensure that the voice of the channel is heard.
The Channel Gateway fully supports tape libraries and streams data at channel speed between mainframe channels and the Fibre Channel network.
However, because growth in the channel continues to outpace growth in direct sales for many industries the need for visibility into the channel is critical to maximizing profitability," said Denis Pombriant, managing principal, Beagle Research Group, LLC.
The channel is available nationwide on Dish Network, and select Time Warner, Comcast, Cox and other cable systems.