SON

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SON

A gene on chromosome 21q22.11 that encodes an RNA-binding protein which acts as a mRNA splicing cofactor by promoting efficient splicing of cell cycle and DNA-repair transcripts (e.g., TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A and FANCG), which possess weak splice sites. SON also binds to DNA and may indirectly repress hepatitis-B virus (HBV) core promoter activity, as well as transcription of HBV genes and production of HBV virions.
References in classic literature ?
63-66) But from Euboea Elephenor, leader of men, the son of Chalcodon, prince of the bold Abantes, sought her to wife.
And the sons of Aeolus, kings dealing justice, were Cretheus, and Athamas, and clever Sisyphus, and wicked Salmoneus and overbold Perieres.
but there was no deceitful dealing in the sons of Tyndareus.
In an argument between the son of Death & the son of Wisdom--
Son is the progeny of sharecroppers; Tom is the son of Conrad Coleman, the man who owns the land on which the black boy's family farms and lives.
Fred Craddock points out that a great deal of preaching on the parable from Luke focuses on the son instead of the main character, the father.
Like an analysand working over the family in absentia, the son envelops his father's Myth in history: "Film created the opportunity to have a dialogue with him, even though he's been dead for thirty years" is how he puts it.
10) The debate about the messianic identity of the Son of Man is still open, with scholars struggling to reach an agreement.
Rebekah marries the son of Abraham and Sarah, Isaac.
And the court's decision to grant a visitation between the son and his father - who had a history of domestic violence - dumbfounds advocates who say these laws must be changed.
He was noted as the son of Marja Goncalves, a widow who sold bread in the market square.
Raffaello Borghini, the first writer to mention Pulzone's work in Il riposo of 1584, described it as a painting of the Virgin and angels among clouds; below are some saints and a young boy -- a portrait taken from life of the son of the Marchese of Riano, patron of the painting.