T helper cell

(redirected from Th2 cell)

T helper cell

see helper lymphocyte.
References in periodicals archive ?
MCP-1 is involved in the defect of Th2 cell polarity [8] and also affects the generation of interleukin-4 (IL-4), interferon-[gamma] (IFN-[gamma]), and interleukin-12 (IL-12).
Asthma is considered a Th2 cell mediated disease which is instigating many current therapeutic strategies.
In addition, the stimulatory effect of IL-12 on Th1 development is antagonized by IL-4, a cytokine which promotes Th2 cell development.
As a characteristic cytokine of Th2 cell, IL-4 could promote the occurrence and development of inflammatory reactions characterized by Th2 [13].
3 If monocyte/macrophage releases IL-10 continuously, it will result in division of Th cell to Th2 cell.
Activation of eosinophils via IgA or Th2 cell mediation stimulates production and degranulation of the marrow and existing eosinophils.
In addition to TGF-[beta], IL-4 production drives Th2 cell development and B cell IgA antibody production.
In conclusion, Th2 cell activation and T regulatory cell deficiency are key features of allergy.
Th2 cell proliferation and the overexpression of cytokines would play an essential role in the development of the disease.
IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation.
An activated Th2 cell acts on B-cells in the area to trigger their activation and "class switching" to secrete IgE.
1,25(OH)2D3 decreases Thl cell cytokines, but increases secretion of IL-4 which is one of the Th2 cell cytokines.