T helper cell

(redirected from Th2)
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T helper cell

see helper lymphocyte.
References in periodicals archive ?
IL-4, a glycoprotein produced by Th2 cells, natural killer cells, mast cells, and basophils, promotes Th2 development.
Although it was previously considered to be produced primarily by Th2 cells, evidence now indicates that KC also produce IL-10, and that KC-derived IL-10 has an important immunoregulatory function (Enk & Katz 1992).
As a nutritional supplement, liquid thymus extracts have proven to be beneficial in restoring the balance between THl and TH2 cells that can be altered in many conditions, including allergies.
Coupled with airway inflammation, T cells in the airways in human and animal models of allergic asthma present cytokine profiles characteristic of Th2 cells (Zissler et al.
Th2 cytokines (IL-4, IL-5, IL-13) induce allergen-specific immunoglobulin (Ig) E production and inflammatory mediator release from mast cells (2).
14,26,27) The Th2 cytokines IL-4 and IL-13 both signal in part through IL-4 receptor [alpha] on keratinocytes, fibroblasts, and other cells to promote B cell differentiation, enhance class switching to immunoglobulin E antibodies, and reduce filaggrin and ceramide expression.
Fighting the flu virus requires a highly coordinated immune response called Th1, whereas fighting harmless allergens (dander, pollen) is called Th2.
Furthermore, in vitro we investigated mRNA expression for IL-22 and IL-22 BP, and IL 22 receptor after co-stimulation of peripheral blood mononuclear cells (PBMC) from individuals with asthma and normal controls with Th2 cytokines IL-4, IL-9, and GM-CSF in a time-dependent manner.
Moreover, the profile of Th1 (IFN-[gamma]) and Th2 (IL-4) cytokine gene expression was analyzed.
El primer analogo funcionalmente distinto de [alfa]GalCer fue identificado como OCH, el cual produce una respuesta con tendencia al tipo Th2 similar a otros analogos como C20:2, que tiene una cadena acilada mas corta e insaturada (26,27).
3) Treg cells, which secrete transforming growth factor (TFG)-(3, and Th2 cells, which release IL-4, were thought to be important in diseases amelioration.
In skin lesions of acute AD, activated Th2 cells would induce B cells to produce IgE by releasing cytokines such as IL-4 [9, 12].