T helper cell

(redirected from Th1 cell)

T helper cell

see helper lymphocyte.
References in periodicals archive ?
14) Accordingly, IL-33 may be involved in the pathogenesis of the EAE and MS through the reinforcement of Th17 and Th1 cell functions.
ABIVAX has access to a number of cutting edge technologies including RNA-protein interaction Interference, B cell and cytotoxic TH1 cell amplification which it is using to generate proprietary breakthrough therapies to help patients clear important pathogenic viruses.
miR-19b has been shown to have a critical role in promoting Th1 cell responses and in suppressing inducible regulatory T-cell differentiation via targeting phosphatase and tensin homolog (PTEN) (16).
Vitamin D or VDR deficient hosts have high Th1 cell cytokine levels, although they have low levels of Th2 cell cytokines.
IL-10, an anti-inflammatory cytokine, is a potent inhibitor of IFN[gamma] synthesis and of Th1 cell kindling.
Th2 dominated immunity is associated with increased susceptibility to the disease, while Th1 cell activation is assumed to induce protective immunity (7-9).
Most of the patients have impaired cytokine production by the TH1 cell population and this includes IL-12, IL-2 and IFN[gamma].
Cytokines produced by Th1 cell activation--namely interleukin 2 and interferon-[gamma]--suppress Th2 cells, while the Th2 cytokines (interleukins 2, 5, and 10) exert an anti-inflammatory effect by suppressing Th1.
The bacterial or viral nucleotides will attract a TH1 cell rather than the TH2 type.
Results: The Th1 cell percentage and Th2/Th1 ratio in the HBV infection group (including IT, IC, and AHB groups) were significantly different from those in HI group (24.
The increasing level of IFN-[gamma] may contribute to SLE pathogenesis by inducing B cell activating factor (BAFF) production, MHC I/II expression, and initiating Th1 cell response [76].
If monocyte/macrophage releases IL- 12 continuously, it will promote transformation of Th cell to Th1 cell.