T helper cell

(redirected from Th1 cell)

T helper cell

see helper lymphocyte.
References in periodicals archive ?
ABIVAX has access to a number of cutting edge technologies including RNA-protein interaction Interference, B cell and cytotoxic TH1 cell amplification which it is using to generate proprietary breakthrough therapies to help patients clear important pathogenic viruses.
miR-19b has been shown to have a critical role in promoting Th1 cell responses and in suppressing inducible regulatory T-cell differentiation via targeting phosphatase and tensin homolog (PTEN) (16).
Vitamin D or VDR deficient hosts have high Th1 cell cytokine levels, although they have low levels of Th2 cell cytokines.
IL-10, an anti-inflammatory cytokine, is a potent inhibitor of IFN[gamma] synthesis and of Th1 cell kindling.
Th2 dominated immunity is associated with increased susceptibility to the disease, while Th1 cell activation is assumed to induce protective immunity (7-9).
Most of the patients have impaired cytokine production by the TH1 cell population and this includes IL-12, IL-2 and IFN[gamma].
Cytokines produced by Th1 cell activation--namely interleukin 2 and interferon-[gamma]--suppress Th2 cells, while the Th2 cytokines (interleukins 2, 5, and 10) exert an anti-inflammatory effect by suppressing Th1.
BioVant, on the other hand, elicits a biased Th1 cell response with concurrent Th2 response, the combination of which activates T lymphocytes that destroy virally infected cells and which promotes antibody immunity.
After 6 months of exercise, the IFN-gamma-associated TH1 cell subtypes increased significantly by close to 35%, while IL-4 associated TH2 cells did not change.
BioVant, on the other hand, elicits a biased Th1 cell response with concurrent Th2 response, the combination of which activates T lymphocytes that destroy virally infected cells and promotes antibody immunity -- and can be adjusted to enhance either type of response to meet specific clinical needs.
ABIVAX utilises a technology platform leveraging RNA-protein interaction Interference, B cell and cytotoxic TH1 cell amplification to generate proprietary breakthrough therapies that are designed to help patients clear important pathogenic viruses such as HIV, HBV and HPV.
Interestingly an extract from green tea Camellia sinensis increases expression of Th1 cell specific bio-markers, which counteracts the dominance of Th2 cells markers typically seen in the ovalbumin-induced asthmatic model (Heo et al.