tetrahydrofolic acid

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tet·ra·hy·dro·fo·lic ac·id (FH4),

(tet'ră-hī'drō-fō'lik as'id),
The active coenzyme form of folic acid; participates in one-carbon metabolism.
Synonym(s): coenzyme C, coenzyme F
Farlex Partner Medical Dictionary © Farlex 2012

tet·ra·hy·dro·fo·lic ac·id

(THFA) (tet'ră-hī-drŏ-fō'lik as'id)
The active form of folic acid, which can donate four formyl groups during DNA synthesis.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
In folate pathway mechanism deoxythymidine monophosphate (dTMP) (dTMP) is produced from deoxyuridine monophosphate (dUMP) by oxidation of tetrahydrofolate to dihydrofolate catalysed by dihydrofolate reductase (DHFR) (Hyde 2005; Abali et al.
Etude du Polymorphisme C677T du Gene de la Methylene Tetrahydrofolate Reductase dans la Population Tunisienne.
In this assay, DHFR catalyzes the reduction of dihydrofolate (F[H.sub.2]) to tetrahydrofolate in the presence of NADPH, which is oxidized to [NADP.sup.+].
Moreover, the T allele of the MTHFR gene has been associated with an accumulation of formylated tetrahydrofolate in red blood cells, which is not the normal form of RCF (12).
With the preferred substrate tetrahydrofolate (THF), [1] glutamate chain-length elongation is rapid up to a glutamate chain length of five glutamate residues.