tetrahydrofolic acid

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tet·ra·hy·dro·fo·lic ac·id (FH4),

(tet'ră-hī'drō-fō'lik as'id),
The active coenzyme form of folic acid; participates in one-carbon metabolism.
Synonym(s): coenzyme C, coenzyme F

tetrahydrofolic acid

/tet·ra·hy·dro·fo·lic ac·id/ (-hi″dro-fo´lik) a form of folic acid in which the pteridine ring is fully reduced; it is the parent compound of a variety of coenzymes that serve as carriers of one-carbon groups in metabolic reactions; in dissociated form, called tetrahydrofolate. Abbreviated THF.

tet·ra·hy·dro·fo·lic ac·id

(THFA) (tet'ră-hī-drŏ-fō'lik as'id)
The active form of folic acid, which can donate four formyl groups during DNA synthesis.
References in periodicals archive ?
In folate pathway mechanism deoxythymidine monophosphate (dTMP) (dTMP) is produced from deoxyuridine monophosphate (dUMP) by oxidation of tetrahydrofolate to dihydrofolate catalysed by dihydrofolate reductase (DHFR) (Hyde 2005; Abali et al.
Etude du Polymorphisme C677T du Gene de la Methylene Tetrahydrofolate Reductase dans la Population Tunisienne.
Moreover, the T allele of the MTHFR gene has been associated with an accumulation of formylated tetrahydrofolate in red blood cells, which is not the normal form of RCF (12).
With the preferred substrate tetrahydrofolate (THF), [1] glutamate chain-length elongation is rapid up to a glutamate chain length of five glutamate residues.