tetracyclic antidepressant

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tet·ra·cy·clic an·ti·de·pres·sant

a class of antidepressants similar to the tricyclic antidepressants and also related to the phenothiazine antipsychotics.

tetracyclic antidepressant

(tĕt′rə-sī′klĭk, -sĭk′lĭk)
n.
Any of a class of antidepressants, such as maprotiline, whose chemical structure includes four benzene rings.

tetracyclic antidepressant

Any of a class of antidepressant agents whose chemical structure has four fused rings. These drugs block the reuptake of norepinephrine and serotonin at nerve endings.
See also: antidepressant
References in periodicals archive ?
The global anxiety disorders and depression treatment market segmentation is based on drug class (selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake, atypical antipsychotics, tricyclic antidepressants, tetracyclic antidepressants, monoamine oxidase inhibitors, benzodiazepines, beta-blockers, anticonvulsants).
The antidepressants currently prescribed for the treatment of MDD comprise eight main classes: The monoamine oxidase inhibitors (MAOIs), norepinephrine-dopamine reuptake inhibitors (NDRIs), serotonin modulators (SM), noradrenergic and specific serotonergic antidepressants (NaSSAs), serotonin-norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSRIs), tricyclic antidepressants (TCAs), and tetracyclic antidepressants (TeCAs).
Sexual side effects are most often associated with serotonin and norepinephrine reuptake inhibitors (SNRIs), selective serotonin reuptake inhibitors (SSR1s), monoamine oxidase inhibitors (MAOIs) and tricyclic and tetracyclic antidepressants.
Randomized placebo-controlled trials with tricyclic and tetracyclic antidepressants (TCAs), selective serotonin reuptake inhibitors (SSRIs), serotonin and noradrenaline reuptake inhibitors (SNRIs), and monoamine oxidase inhibitors (MAOIs) were analyzed.
Tricylcic and tetracyclic antidepressants (TCAs) also can result in dryness in the mouth and nasal mucosa and also contribute to gastroesophageal reflux.
For example, decreased libido has been reported in studies examining the sexual side effects of tricyclic and tetracyclic antidepressants, monoamine oxidase inhibitors, and SSRIs.
John's wort for one to three months with subjects who received placebo or antidepressant therapy with medications such as tricyclic or tetracyclic antidepressants and selective serotonin reuptake inhibitors (SSRIs) for the same period.
Amitriptyline and other tricyclic and tetracyclic antidepressants moderately improve pain control for patients with chronic back pain.
25] Current treatment options include traditional tricyclic antidepressants, monoamine oxidase inhibitors (MAOIs), tetracyclic antidepressants (eg, maprotiline), and selective serotonin reuptake inhibiting (SSRI) antidepressants (Table 2).