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Related to terfenadine: Astemizole
terfenadineA non-sedating antihistamine used for allergies and viral upper respiratory tract infections. It is available in Canada, the UK, and in some other countries by prescription, but was withdrawn from US market due to cardiotoxicity.
Arrhythmias (e.g., torsades de pointes, which may be due to delayed repolarisation with marked QT prolongation) and bizarre T-wave changes.
terfenadineSeldane® A non-sedating antihistamine used for allergy and viral URIs Adverse effects Arrhythmias–eg, torsades de pointes; should not be combined with ketoconazole, an antifungal that alters its metabolism, resulting in accumulation of the parent compound, a K+ channel blocker that prolongs QT. See Allegra.
terfenadineA non-sedating antihistamine drug used to treat ALLERGIC RHINITIS and URTICARIA. The drug can cause heart irregularities and should not be used by people with heart or liver disease. It should not be taken with grapefruit juice which increases its bioavailability.
a nonsedating antihistamine used in the treatment of allergies.