tenofovir disoproxil


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tenofovir disoproxil

An antiviral drug of the nucleotide analogue reverse transcriptase inhibitor class. It is used in combination with other ani-HIV drugs mainly to treat HIV infections that have shown reduced sensitivity to other treatment regimens. A brand name is Viread.
References in periodicals archive ?
Lactic acidosis and hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues including lamivudine and tenofovir disoproxil fumarate.
As a new antiviral drug for CHB, tenofovir disoproxil (TDF) has recently been recommended as the first line of anti-HBV NAs medication by domestic and international CHB prevention and treatment guidelines.
Compared to formulations containing tenofovir disoproxil fumarate, the newer tenofovir alafenamide formulation achieves higher intracellular levels in CD4 lymphocytes (but not in renal tubular cells).
Daily tenofovir disoproxil fumarate / emtricitabine is recommended for use as preexposure prophylaxis to prevent HIV infection in persons at high risk.
8) This study was aimed at documenting and analysing the adverse effect profile of Tenofovir Disoproxil Fumarate-based ART in HIV positive patients attending ART Centre, Government Medical College, Thrissur.
Tenofovir disoproxil fumarate {9-[(R)-2-[[bis [[isopropoxycarbonyl] oxy] methoxy] phosphonyl] methoxy] propyl] adenine fumarate} is a nucleotide analog reverse transcriptase inhibitor (NRTI) and is used for treating HIV infection in adults, in combination with other antiretroviral agents [3, 4].
Emtricitabine is marketed by Gilead under the brand name Emtriva, and a fixed-dose combination of Emtricitabine and Tenofovir Disoproxil Fumarate is made available under the brand name Truvada.
On October 26 the FDA approved Viread (tm) -- generic name tenofovir disoproxil fumarate, or tenofovir DF.
Contract notice: supply of emtricitabine 200 mg / tenofovir disoproxil 245 mg tablets c / 30 to the penitentiary centers dependent on the general secretariat of penitentiary institutions