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Detection of mitochondrial DNA mutations by temporal temperature gradient gel electrophoresis. Clin Chem 1999;45:1162-7.
Rapid detection of FGFR mutations in syndromic craniosynostosis by temporal temperature gradient gel electrophoresis. Clin Chem 1999;45:2005-6.
Results of Southern Blot Analysis of T-Cell Receptor (TCR)-[Beta] and Temperature Gradient Gel Electrophoresis Analysis of TCR[Gamma], for TCR Gene Rearrangement in Various Lymphoid Disorders(*) Diagnosis (N = 118) SB TGGE T-cell neoplasms (n = 58) 58 54 CTCL (n = 11) PTCL (n = 40) LGL (n = 3) PLL (n = 2) PTLD (n = 2) B-cell neoplasms (n = 38) 0 1 CLL/SLL (n = 11) FL (n = 7) MCL (n = 2) MALToma (n = 4) LCL (n = 14) Reactive (n = 22) 0 0
Temperature gradient gel electrophoresis was performed by a vertical acrylamide slab-gel apparatus (Decode System, BioRad, Hercules, Calif).
It must be noted that TTGE differs from temperature gradient gel electrophoresis. In TTGE, a temporal temperature gradient is established.
Identification of mutations and polymorphisms in the COL2A1 gene by temporal temperature gradient gel electrophoresis [Abstract].
We report the rapid and inexpensive detection of FGFR mutations by a relatively novel screening assay, temporal temperature gradient gel electrophoresis (TTGE).
(3) describe the application of temporal temperature gradient gel electrophoresis to the detection of mtDNA mutations and show that this technique offers great promise in this application.
Commonly used screening methods include denaturing gradient gel electrophoresis (DGGE) (5), temperature gradient gel electrophoresis (TGGE) (6), singlestranded conformation polymorphism, heteroduplex analysis (HA), chemical mismatch cleavage, enzyme mismatch cleavage (EMC), the protein truncation test, mismatch-binding protein, and cleavase fragment length polymorphism.
Temporal temperature gradient gel electrophoresis (TTGE) was first introduced by Yoshino et al.
Rapid and simple subtyping of the HLA-DRB3 gene in Graves' disease using temperature gradient gel electrophoresis. Hum Immunol 1993;36:199-203.
Rapid screening for Tp53 mutations by temperature gradient gel electrophoresis: a comparison with SSCP analysis.

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