Living With HHT: Understanding and Managing Your Hereditary Hemorrhagic Telangiectasia
Kelly, MD, listed her preferred light-based treatment options for telangiectasias
as the pulsed-dye laser (PDL), the 532-nm Nd:YAG laser, and the diode laser.
Hereditary hemorrhagic telangiectasia
(HHT) is an autosomal dominant systemic disorder of angiogenesis characterized by vascular malformations in mucocutaneous tissues, visceral organs, and the central nervous system (1).
Fundoscopic examination showed perifoveolar hard exudates and telangiectasias
in the left eye (Fig.
Swift, "Mortality rates among carriers of ataxia- telangiectasia
mutant alleles," Annals of Internal Medicine, vol.
Los criterios son: sangrado nasal espontaneo y recurrente, telangiectasias
, historia familiar, lesiones viscerales.
CASE HISTORY: A 20years old male, a known case of hereditary haemorrhagic telangiectasia
, suffering from recurrent skin lesions and infections was on treatment for the last 12years.
may be differentiated from the other CNS vascular malformations in that they are usually benign, asymptomatic, and small, ranging from a few millimeters to 2 cm (1,2,3) in size.
Morphological features included epidermal atrophy in 90%, erythema in 55%, follicular plugging in 40%, telangiectasia
The technique has undergone further modifications, but it generally seems to truly eliminate epistaxis, although later minor interventions are necessary to eliminate peripheral telangiectasias
No tachyphylaxis or rebound worsening of erythema occurred during the off-treatment follow-up, nor did the brimonidine tartrate group experience aggravation of telangiectasias
or inflammatory lesions during that phase of the study, according to Dr.
EGCG topical treatments influence HIF-1 [alpha] induction and VEGF expression and may serve as a potential agent in the prevention of telangiectasias