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the quantity to be administered at one time, as a specified amount of medication or a given quantity of radiation.
absorbed dose that amount of energy from ionizing radiations absorbed per unit mass of matter, expressed in rads.
air dose the intensity of an x-ray or gamma-ray beam in air, expressed in roentgens.
booster dose an amount of immunogen (vaccine, toxoid, or other antigen preparation), usually smaller than the original amount, injected at an appropriate interval after primary immunization to sustain the immune response to that immunogen.
curative dose (CD) a dose that is sufficient to restore normal health. See also median curative dose.
divided dose fractionated dose.
effective dose (ED) that quantity of a drug that will produce the effects for which it is administered. See also median effective dose.
erythema dose that amount of radiation that, when applied to the skin, causes erythema (temporary reddening).
fatal dose lethal dose.
fractionated dose a fraction of the total dose prescribed, as of chemotherapy or radiation therapy, to be given at intervals, usually during a 24-hour period.
infective dose (ID) that amount of a pathogenic agent that will cause infection in susceptible subjects. See also median infective dose and tissue culture infective dose.
lethal dose (LD) that quantity of an agent that will or may be sufficient to cause death. See also median lethal dose and minimum lethal dose.
loading dose a dose of medication, often larger than subsequent doses, administered for the purpose of establishing a therapeutic level of the medication.
maintenance dose the amount of a medication administered to maintain a desired level of the medication in the blood.
maximum tolerated dose tolerance dose.
maximum permissible dose the largest amount of ionizing radiation that one may safely receive within a specified period according to recommended limits in current radiation protection guides. The specific amounts vary with age and circumstance.
median curative dose (CD50) a dose that abolishes symptoms in 50 per cent of test subjects.
median effective dose (ED50) a dose that produces the desired effect in 50 per cent of a population.
median infective dose (ID50) that amount of pathogenic microorganisms that will produce demonstrable infection in 50 per cent of the test subjects.
median lethal dose (LD50) the quantity of an agent that will kill 50 per cent of the test subjects; in radiology, the amount of radiation that will kill, within a specified period, 50 per cent of individuals in a large group or population.
median tissue culture infective dose (TCID50) that amount of a pathogenic agent that will produce infection in 50 per cent of cell cultures inoculated.
minimum lethal dose
1. the amount of toxin that will just kill an experimental animal.
2. the smallest quantity of diphtheria toxin that will kill a guinea pig of 250-gm weight in 4 to 5 days when injected subcutaneously.
reference dose an estimate of the daily exposure to a substance for humans that is assumed to be without appreciable risk; it is calculated using the no observed adverse effect level and is more conservative than the older margin of safety.
skin dose (SD)
1. the air dose of radiation at the skin surface, comprising the primary radiation plus backscatter.
2. the absorbed dose in the skin.
threshold dose the minimum dose of ionizing radiation, a chemical, or a drug that will produce a detectable degree of any given effect.
threshold erythema dose (TED) the single skin dose that will produce, in 80 per cent of those tested, a faint but definite erythema within 30 days, and in the other 20 per cent, no visible reaction.
tissue culture infective dose (TCID) that amount of a pathogenic agent that will produce infection when inoculated on tissue cultures; used with a numeric qualifier.
tolerance dose the largest quantity of an agent that may be administered without harm. Called also maximum tolerated dose.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
(Teddy Boy) with a knife on the arms of four schoolmates burst into tears at West London Juvenile Court yesterday when told he was going to be sent to an approved school.
In time, the ultimate Teddy Boy look mirrored that of the Bowery B'hoys by distinguishing its wearer as a novel social type:
"If diplomacy is the ability to tell someone to go to hell in such a way that he looks forward to the trip, Teddy Boy has this skill in abundance.
The Ted went to Ellen, and he hugged her, and although she was poorly, she cried out: "Tony!" The Teddy boy and Ellen passed Mr Jones dancing and laughing, and left the ward.
Police Inspector J Penninghton said of him and his two colleagues: "They are the hard-core of a local gang of Teddy Boy ruffians, of which Kelly, a lazy and low-class bully, is the leader.
Fogs "At a time when 'Teddy boy' gear, Saturday morning matinees at the local 'flicks', Hula Hoops and flared skirts were popular, lives would be interrupted by the sudden appearance of fogs - dense blankets of sulphurous pollution that brought visibility almost to zero.
The former England captain looked like a British Teddy Boy in the snaps taken for glossy mag Fantastic Man.
We ended up having a drink at the Teddy Boy milk bar.
I took my girlfriend Margaret, now my wife of 40 years, to see her favourites and Cliff was resplendent in a pink "Teddy Boy" outfit.
Groom Les, actor Bruce Jones, wasn't the traditional groom either in Teddy Boy jacket with drainpipe trousers.
Foreign Affairs Secretary Teodoro 'Teddy Boy' Locsin Jr.
The Catholic Bishops' Conference of the Philippines-Episcopal Commission on Migrants and Itinerant People (CBCP-ECMI) has appealed to newly appointed Secretary of the Department of Foreign Affairs Teodoro "Teddy Boy" Locsin Jr.