Teardrop Cell

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A deformed RBC which is tugged to a nipple at one end, having squeezed through a reticuloendothelial system with increased connective tissue
Aetiology Myelofibrosis, and other reticuloendothelial replacement disorders that compromise the bone marrow space, causing splenic overload or decreased functional splenic tissue—e.g., megaloblastic anaemia, hereditary elliptocytosis, anaemia of renal disease, haemolytic anaemias, sickle cell anaemia, thalassemia, and bone marrow infiltration by haematologic and non-haematologic malignancies may also be accompanied by dacrocytosis. Tear drop cells are also seen in normal peripheral blood smears as an artefact of slide preparation; such dacrocytes are usually easily recognised as their 'tails' all point in the same direction
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


An abnormally shaped red blood cell with a single point or elongation. This form of poikilocyte is associated with myelofibrosis with myeloid metaplasia.
Synonym(s): teardrop cell.
[dacryo- + -cyte]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
For instance, myelofibrosis can be quickly diagnosed using this integrated manner using cytopenia(s) as criterium/criteria in combination with the detection of teardrop cells. Remote review of both the cell counter results and the morphological pre-classification by the digital microscope can be performed by a laboratorian using a computer screen, integrating both results.
[16] in their cases found rare to moderate numbers of teardrop cells, rare nucleated RBCs with moderately reduced to normal platelet counts, mild to moderate anemia, and normal to mild reduction in the leukocyte counts.
The red cell morphology showed anisocytosis, poikilocytosis with occasional teardrop cells, spherocytes, ovalocytes, and a few schistocytes.
Peripheral blood showed moderate macrocytosis with occasional microcytes, elliptocytes and occasional teardrop cells. No nucleated red blood cells (RBCs) were seen.
Notably, the presence of spherocytes (hemolysis), teardrop cells (myelofibrosis, bone marrow metastases), or sickle cells (sickle-cell anemia), as examples, give information beyond that of the standard indices.
We've eliminated "occ'l" when describing elliptocytes, target cells, burr cells, schistocytes, acanthocytes, and teardrop cells. These cell types should be present in significant numbers -- i.e., "few," "mod," or "many" -- or not reported at all.