Teardrop Cell

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A deformed RBC which is tugged to a nipple at one end, having squeezed through a reticuloendothelial system with increased connective tissue
Aetiology Myelofibrosis, and other reticuloendothelial replacement disorders that compromise the bone marrow space, causing splenic overload or decreased functional splenic tissue—e.g., megaloblastic anaemia, hereditary elliptocytosis, anaemia of renal disease, haemolytic anaemias, sickle cell anaemia, thalassemia, and bone marrow infiltration by haematologic and non-haematologic malignancies may also be accompanied by dacrocytosis. Tear drop cells are also seen in normal peripheral blood smears as an artefact of slide preparation; such dacrocytes are usually easily recognised as their 'tails' all point in the same direction


An abnormally shaped red blood cell with a single point or elongation. This form of poikilocyte is associated with myelofibrosis with myeloid metaplasia.
Synonym(s): teardrop cell.
[dacryo- + -cyte]
References in periodicals archive ?
Section II discusses the specifics of grading individual red blood cell abnormalities and defines a grading system described in words and images for anisocytosis, poikilocytosis, microcytosis, macrocytosis, hypochromia, polychromasia, blister cells, target cells, teardrop cells, schistocytes, sickle cells, spherocytes, acanthocytes, echinocytes, elliptocytes, stomatocytes, Howell-Jolly bodies, basophilic stippling, Pappenheimer bodies, rouleaux, and agglutination.
16] in their cases found rare to moderate numbers of teardrop cells, rare nucleated RBCs with moderately reduced to normal platelet counts, mild to moderate anemia, and normal to mild reduction in the leukocyte counts.
Notably, the presence of spherocytes (hemolysis), teardrop cells (myelofibrosis, bone marrow metastases), or sickle cells (sickle-cell anemia), as examples, give information beyond that of the standard indices.
We've eliminated "occ'l" when describing elliptocytes, target cells, burr cells, schistocytes, acanthocytes, and teardrop cells.