SPINK1

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SPINK1

A gene on chromosome 5q32 that encodes a trypsin inhibitor secreted from pancreatic acinar cells into pancreatic juice. SPINK1 is thought to prevent trypsin-catalysed premature activation of zymogens within the pancreas and the pancreatic duct.

Molecular pathology
SPINK1 mutations are associated with hereditary pancreatitis and tropical calcific pancreatitis.
References in periodicals archive ?
TPA, TATI, CEA, AFP, beta-HCG, PSA, SCC, and CA 19 -9 for monitoring transitional cell carcinoma of the bladder.
Tati emphasizes this jarring separation of us from humans who once warmly and personally met eye-to-eye with the next cut--to a startlingly Kubrick-like shot of a long, long corridor, pillars on both sides, ending at a distant, lightbox-ish square that itself seems like a far, far, faraway screen.
Off to the Outer Hebrides, then, and some of the funniest moments of "The Illusionist" as Tati and Chomet dish up a few gentle laughs at the expense of the rustic Scots.
The one Tati I've always been reluctant to share with anyone is "Les vacances de Monsieur Hulot.
yesa€™ and TATI now proudly adds this accreditation to its prestigious position as the only Defensive Driving Training Provider (DDTP) to Petroleum Development Oman (PDO).
He believes Tati - who died in 1982 aged 75 - wrote it out of guilt for spending too long away from Sophie.
Shafira suffered from eczema when she was younger and Tati was always very concerned with how to help her and give advice.
Directed, written by Sylvain Chomet, based on a script by Jacques Tati.
Five French filmmakers; Renoir, Bresson, Tati, Truffaut, Rohmer; essays and interviews.
Hulot (1953) was released as Monsieur Hulot's Holiday in the UK and as Mr Hulot's Holiday in the USA, and established a lasting reputation for its director, Jacques Tati.