targeted therapy

(redirected from Targeted cancer therapy)

targeted therapy

A generic term for therapies that impact on a specific molecular pathway, target or ligand.

Examples
Gefitimib for non-small cell carcinoma of the lungs with mutations in epidermal growth factor receptor, and imatinib for GIST tumours with activating mutations in c-Kit.
References in periodicals archive ?
Jude Children's Research Hospital, Memphis) bring together a group of North American and European specialists in TOR signaling to discuss targeted cancer therapy in the areas of mTOR (mammalian target of rapamycin) signaling and therapeutic targeting downstream of mTOR.
In the framework of a strategic alliance of DKFZ with Bayer-Schering, the researchers in Kramer's team are now planning to look among the identified genes for suitable targets for a targeted cancer therapy.
On February 19, 2002, the FDA approved ZEVALIN, a new type of targeted cancer therapy called radioimmunotherapy, making it the first commercially available radioimmunotherapy for the treatment of B-cell non-Hodgkin's lymphoma (NHL).
This work provides a review of the state of the art of targeted cancer therapy, covering new and emerging technologies in target identification, drug discovery, molecular markers, and imaging.
Includes targeted cancer therapy drug profiles and development overviews detailing the companies involved and the clinical data that led to approvals
Analysis of sales forecasts of 28 targeted cancer therapy brands over the period 2011-21 in the seven major pharmaceutical markets.
Diagnostic tests and even targeted cancer therapy treatments are physically demanding, pain and fatigue and resulting hopelessness is a constant presence in patients' lives.
Sales forecasts of targeted cancer therapy brands over the period 2010-20 in the seven major pharmaceutical markets.
This first targeted cancer therapy, imatinib mesylate, or Gleevec, contributed to a major breakthrough in the treatment of Chronic Myelogenous Leukemia (CML), followed by its successful application to other malignant cancers by turning off the signal of the protein causing these cancers.
For the last few years, ImClone has been sidetracked by legal issues; yet ImClone still claims a legitimate cancer blockbuster: Erbitux, the first targeted cancer therapy approved for colorectal cancer.
A new report by visiongain forecasts that small-molecule targeted cancer therapy revenues will reach $32.
Includes targeted cancer therapy drug profiles and development overviews detailing the companies involved and the clinical data that led to approvals* Includes SWOT analysis of each brand in the targeted cancer therapies class* Overview of each brand's positioning in its marketed indications relative to its competitors and in terms of its ability to meet unmet needs* Analysis of the clinical and commercial attractiveness of the targeted cancer therapies

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