Tamm-Horsfall protein


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.
Related to Tamm-Horsfall protein: Tamm-Horsfall mucoprotein

Tamm-Hors·fall mu·co·pro·tein

(tam hōrs'fahl),
the matrix of urinary casts derived from the secretion of renal tubular cells.

Tamm-Horsfall protein (THP)

Etymology: Igor Tamm, American virologist, 1922-1995; Frank L. Horsfall, American virologist, 1906-1971
a mucoprotein found in the matrix of renal tubular casts. THP is secreted in the loop of Henle.

Tamm-Horsfall protein

An older term, still in wide use, for what is now better known as uromodulin, which is encoded by UMOD on cytogenetic band 16p12.3.

Horsfall,

Frank L., Jr., U.S. physician, 1906-1971.
Tamm-Horsfall mucoprotein - see under Tamm
Tamm-Horsfall protein

Tamm,

Igor, U.S. virologist, 1922-1971.
Tamm-Horsfall mucoprotein - the matrix of urinary casts derived from the secretion of renal tubular cells.
Tamm-Horsfall protein
References in periodicals archive ?
Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication.
Most cases are associated with marked pyelocaliceal inflammation, tissue necrosis, Tamm-Horsfall protein accumulation, calcific debris, and stones, suggesting a pathogenetic link.
Purified Tamm-Horsfall protein eluted predominantly in the excluded volume, and the peak had an extended tail, but there was no significant overlap with albumin (analysis not shown).