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ASTRONAUTAcid Suppression Trial: Ranitidine/Zantac® vs Omeprazole/Prilosec® for NSAID-Associated Ulcer Treatment. A trial comparing ranitidine and omeprazole in healing and preventing gastroduodenal ulcers in patients requiring long-term management with NSAIDs.
Conclusion Omeprazole was more effective than ranitidine, even at lower doses.