TWAR


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Chla·myd·i·a pneu·mo·ni·ae

a species first isolated in 1986 and currently recognized as a common cause of pneumonia, bronchitis, rhinosinusitis, and pharyngitis in both adults and children.
Synonym(s): TWAR

Chlamydia pneumoniae is responsible for about 25% of cases of acute bronchitis and 10% of community-acquired pneumonia. It may also play a role in the genesis of cardiovascular disease and late-onset Alzheimer dementia. Like C. trachomatis and C. psittaci, this organism is an occasional cause of myocarditis and endocarditis. Elevated levels of antibody to C. pneumoniae are found in patients with acute myocardial infarction (MI) and in those showing severe atheroma formation at autopsy significantly more often than in control groups. The organism has been detected by immunocytochemistry, polymerase chain reaction, and electron microscopy in macrophages and smooth muscle cells of atheromatous plaques of the aorta, coronary arteries, and carotid arteries (surgical and autopsy specimens), but not in normal arteries. The incidence of acute infection in MI patients, as detected by throat culture, is higher than in the general public. A retrospective review of medical records of patients with acute MI showed that they were less likely than matched controls to have been treated during the preceding 3 years with tetracycline or quinolone antibiotics, which are active against C. pneumoniae. To date, however, prospective studies have not shown an association between the presence of IgG antibody to C. pneumoniae and an increased risk of atherothrombotic disease. The current body of evidence favors infection with C. pneumoniae as one of several factors capable of initiating changes that culminate in atherosclerosis. Limited studies suggest that antibiotic treatment may reduce the risk of recurrent coronary events, but have not shown benefits in stable coronary artery disease. Antibody to C. pneumoniae is also found in patients with severe hypertension at about twice the incidence rate for the general public, and has been linked statistically to accelerated loss of lung function in patients with asthma. In addition, the organism has been detected in microglia and astroglia of the hippocampus and temporal cortex in patients with late-onset Alzheimer disease with much greater frequency than in normal brains.

TWAR

(twahr)
[Acronym derived from the laboratory designations of the first two isolates, TW-83 and AR-39]
Synonym(s): Chlamydia pneumoniae.
References in periodicals archive ?
UPBL chairman Glenn Alatraca said everyone was welcome to donate during games on Friday at the Al Twar 2 Sports Hall, Al Twar, Dubai.
The Astronomy Group has set up four large telescopes on the grounds of the New World Private School in Twar for free viewing of the year's first partial solar eclipse.
Serological evidence of an association of a novel Chlamydia, TWAR, with chronic coronary heart disease and acute myocardial infarction.
Addressing the meeting, Qatar Chambers First Vice Chairman, Mohammad bin Ahmad bin Twar al Kuwari said that Qatar and Argentina enjoy good economic and commercial relations, noting that their bilateral trade volume reached $335 mn last year He underscored the importance of HH the Amir's visit to Latin America last year including Argentina which stressed HH's interest to expand Qatar's economic and political relations and its strategic partnerships with Argentina.
The two dialyses centres will be opened in Al Barsha and Al Twar. "The Barsha Dialysis Centre is expected to be completed in 2019, and will operate in two shifts with 60 beds covering around 120 patients a day.
He added that Canton Fair 2018 aimed to "promote its role as a vital platform for strong trade opportunities and to create a better business environment and a more open market to the world." QC first vice-chairman Mohamed bin Ahmed bin Twar highlighted the importance of the strong economic and trade relations between the private sectors in Qatar and China.
Customer happiness centers at Al Manarah Center and Al Twar new center will operate on Thursday, September 21 from 9:00am to 1:00pm.
As part of the ongoing collaboration between the two entities, Dubai Culture hosted an awareness corner at the Al Twar branch of Dubai Public Library to raise public awareness about the importance of preserving the environment.
On Sunday I went to Dubai Municipality Offices in Al Twar to transfer my Dewa account to my new villa.
The Al Twar, Al Lusaily , Nad Al Hamar, Al Mamzar and Al Safa health centres will be open on October 25, 27 and 28 during the morning shift from 8 am to 1 pm, it added.
The MoU was signed by Qatar Chamber's (QC) First Vice-Chairman Mohamed bin Ahmed bin Twar and Jelena Jovanovic, Director of the International Economic Relations Sector at the Chamber of Commerce and Industry of Serbia, in Doha.
Fahad Deshmukh told Gulf News his uncle, Mohiuddin Deshmukh, 85, was found in a mosque in the Al Twar area of Dubai, and people informed the police about his location on Saturday.