TUBA1B

TUBA1B

A gene on chromosome 12q13.12 that encodes an alpha tubulin, which combines with a beta tubulin to form microtubules, acting as a scaffold to determine cell shape and providing a matrix for cell organelle and vesicle movement via motor proteins.
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References in periodicals archive ?
Most of the identified extracellular membrane-bounded organelle proteins such as TUBA1B, ITGB2, UBA1, and ACTB were localized to intracellular and plasma membrane, which suggested that MA has invaded into the cell by attaching to the cell membrane and then affected the expression of the extracellular protein.
Gene name Protein name Average t-test ratio 1 PDIA3 Protein disulfide- 1,5 0,011 isomerase A3 precursor 2 VIM Vimentin 1,8 0,007 3 SELENBP1 Selenium-binding 1,3 0,044 protein 1 4 ENO1 Alpha-enolase 1,4 0,007 5 EIF2S1 Eukaryotic -1,6 0,035 translation initiation factor 2 subunit 1 6 CAPZA1 F-actin capping 1,3 0,028 protein subunit alpha-1 7 PSMA3 Proteasome subunit -1,2 0,026 alpha type 3 8 RPSA 40S ribosomal -1,4 0,023 protein SA 9 ERP29 Endoplasmic 1,4 0,040 reticulum protein ERp29 10 TPI1 Triosephosphate 1,7 0,00009 isomerase 11 PARK7 Protein DJ-1 1,2 0,018 12 tubb Tubulin beta chain -1,7 0,017 13 TUBA1B Tubulin alpha-1B chain -1,9 0,006 14 FABP3 Fatty acid-binding 2,2 0,00035 protein, heart A selection of proteins differentially expressed between primary UM with and without metastasis.
NM_002130) and tubulin, alpha 1b (K-ALPHA-1 or TUBA1B; GenBank accession no.