TSSK2A gene on chromosome 22q11.21 that encodes a testis-specific serine/threonine-protein kinase required during spermatid development. TSSK2 is involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm and required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body; it interacts with TSSK1B. It has been proposed as a target for male contraception or and intra-vaginal spermicides.
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