ACVR1

(redirected from TSRI)
Also found in: Acronyms.

ACVR1

A gene on chromosome 2q23-q24 that encodes activin receptor type I, a receptor that forms a complex with other type-I and two type-II transmembrane serine/threonine kinase receptors for activin, a dimeric growth and differentiating factor belonging to the TGF-beta superfamily of structurally related signalling proteins. Type-II receptors phosphorylate and activate type-I receptors, which autophosphorylate, then bind and activate SMAD transcriptional regulators, playing roles in cell differentiation, growth arrest and apoptosis.

Molecular pathology
ACVR1 mutations are linked to fibrodysplasia ossificans progressive.

References in periodicals archive ?

Chen remarked at the inaugural ceremony that the government had worked on merging the two research labs into TSRI over the past year, in hopes of providing better assistance for industries and other research institutes in Taiwan to better streamline semiconductor research and development processes, and thereby maintain global competitiveness.

Science and Technology Minister sets 3 goals for Taiwan Semiconductor Research Institute

The downgrade to 'A' reflects TSRI's healthy financial profile, evidenced by maintenance of negative pro forma net adjusted debt through a stress scenario, and moderate operating flexibility with solid expense controls.

Fitch Downgrades The Scripps Research Institute (CA) to 'A'; Removes Rating Watch

In work spearheaded by TSRI's Matthew Eddy, PhD, first author of the new study, the researchers used NMR to observe A2aAR in many different conformations, shedding light on how it changes shape on the surface of human cells in response to drug treatments.

New Structure of Key Protein Holds Clues for Better Drug Design

This is yet another exciting application of an incredibly versatile class of catalytic antibodies originally developed by TSRI's Carlos F.

'Double Decker' Antibody Technology Fights Cancer, Scripps Research Institute Study Finds

In 1998, he moved to San Diego as a second postdoc career, and he was a research associate, subsequently a research associate senior, and finally a staff scientist (2002) in the Department of Molecular Biology in The Scripps Research Institute (TSRI), La Jolla, California until 2009.

Folding of apomyoglobin: analysis of transient intermediate structure during refolding using quick hydrogen deuterium exchange and NMR

Walgreens' involvement in the PMI Cohort Program comes from an initial $20 million grant awarded to The Scripps Research Institute (TSRI) by the National Institutes of Health (NIH).

Walgreens joins push to develop individualized medicine

Selexis will develop high-performance research cell banks to manufacture multiple HIV envelope proteins engineered by scientists at IAVI's Neutralizing Antibody Center (NAC) at The Scripps Research Institute (TSRI) and other parts of TSRI to help induce the generation of neutralizing antibodies against HIV through vaccination.

Selexis, IAVI

Precision Medicine Initiative (PMI) Cohort Program through an initial $20 million grant awarded to The Scripps Research Institute (TSRI) by the National Institutes of Health (NIH).

U.S. Precision Medicine effort enlists Walgreens

Vibrent Health has partnered with The Scripps Research Institute (TSRI), which will drive engagement research, participant enrollment of direct volunteers over five years and validation of emerging wearables and medical devices.

VIBRENT FUNDED BY THE NATIONAL INSTITUTES OF HEALTH

ARIZONA (CyHAN)- A group of scientists from Scripps Research Institute (TSRI ) discovered that immune cells able to conquer HIV are present in the human body.