TRPM3


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TRPM3

A gene on chromosome 9q21.12 that encodes a calcium channel upregulated by reduced extracellular osmolarity, store depletion and muscarinic receptor activation.
References in periodicals archive ?
In this project we aim to discover how the channel properties of TRPM3 are regulated at molecular and cellular levels, and how these regulatory mechanisms influence the channels versatile functions in normal sensory transduction and in processes such as itch and hyperalgesia.
This project is expected to reveal important new insight into the cutaneous sensory processes involving TRPM3, which may form the basis of novel therapeutic approaches to treat itch or pain.