thyrotropin-releasing hormone stimulation test(redirected from TRH-stimulation test)
a hormone secreted by the anterior lobe of the pituitary gland that has an affinity for and specifically stimulates the thyroid gland. Called also thyroid-stimulating hormone.
thyrotropin alfa a recombinant form of human thyrotropin; it binds to thyrotropin receptors and stimulates the steps in thyroid hormone synthesis, including iodine uptake and synthesis and secretion of thyroglobulin; used as a diagnostic adjunct in serum thyroglobulin testing, with or without radioiodine scanning, in followup of patients with well-differentiated thyroid cancer, administered intramuscularly.
thyrotropin-releasing hormone stimulation test (thyrotropin-releasing hormone test) a thyroid function test that assesses release of thyrotropin by the pituitary gland; a bolus of thyrotropin-releasing hormone is administered and serum concentrations of thyrotropin are assessed at intervals; if serum levels do not increase within 30 to 40 minutes, the pituitary thyrotrophs are dysfunctional. Called also TRH test and TRH stimulation test.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
thy·rot·ro·pin-re·leas·ing hor·mone stim·u·la·tion test, TRH-stimulation test
a test of pituitary response to injection of thyrotropin-releasing hormone, which normally stimulates pituitary secretion of thyroid-stimulating hormone (TSH, thyrotropin), used primarily to distinguish pituitary from hypothalamic causes of thyroid disorders; TSH does not rise in cases of pituitary dysfunction, but does rise in cases of hypothalamic disorders.
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