TRDMT1

TRDMT1

A gene on chromosome 10p15.1 that encodes a protein that methylates aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop; it also has some DNA-(cytosine-C5) methyltransferase activity.
References in periodicals archive ?
[34,36,37] It is expressed that increased TRDMT1, which takes part in the recognition of DNA damage, DNA recombination, and repair, can influence RNA methylation and affect the development of lung cancer.
Hsa_circ_001242, with a spliced sequence length of 713bp, associated gene symbol is TRDMT1 (tRNA aspartic acid methyltransferase 1) and composed of six exons from exon 3 to exon 8.
Steegers-Theunissen et al., "An association study of 45 folate-related genes in spina bifida: involvement of Cubilin (CUBN) and tRNA Aspartic Acid Methyltransferase 1 (TRDMT1)," Birth Defects Research A--Clinical and Molecular Teratology,vol.