[34,36,37] It is expressed that increased TRDMT1
, which takes part in the recognition of DNA damage, DNA recombination, and repair, can influence RNA methylation and affect the development of lung cancer.
Hsa_circ_001242, with a spliced sequence length of 713bp, associated gene symbol is TRDMT1
(tRNA aspartic acid methyltransferase 1) and composed of six exons from exon 3 to exon 8.
Steegers-Theunissen et al., "An association study of 45 folate-related genes in spina bifida: involvement of Cubilin (CUBN) and tRNA Aspartic Acid Methyltransferase 1 (TRDMT1
)," Birth Defects Research A--Clinical and Molecular Teratology,vol.