thrombopoietin

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thrombopoietin

 [throm″bo-poi´ĕ-tin]
a colony-stimulating factor that is the humoral regulator of the production of platelets.

throm·bo·poi·e·tin

(throm'bō-poy'ĕ-tin), [MIM*600044]
A cytokine that serves as a humoral regulator for the production of blood platelets through action on the receptor c-mp1.
[thrombo- + G. poiētēs, maker, + in]

throm·bo·poi·e·tin

(throm'bō-poy'ĕ-tin)
A cytokine that serves as a humoral regulator for the production of blood platelets through action on the receptor c-mp1.
Synonym(s): megakaryocyte growth and development factor, megapoietin.
[thrombo- + G. poiētēs, maker, + in]

thrombopoietin

A hormone responsible for the growth of colonies of megakaryocytes and the production of platelets. The existence of thrombopoietin has been suspected for 30 years but was realized only in 1994. In 1997 the results of a trial of polyethylene-conjugated genetically-engineered (recombinant) thrombopoietin-described as recombinant human megakatyocyte growth and development factor (PEGrHuMGDF)-was published. It was found to have a powerful stimulatory effect on PLATELET production. Thrombopoietin is the ligand for the cytokine receptor Mpl.
References in periodicals archive ?
Regarding the distribution of thyroid AB according to HBAC1 group, there was progressive positive anti TPO titer with glycemic status; Good glycemic control had the lowest positive anti TPO titer and poor glycemic control group had the highest positive anti TPO titer and the result was statistically significant (p=0.048), as shown in (Table-III).
In September 2014, after due consideration of all implications related to TPO, the FIFA Executive Committed passed a general principle of a ban on TPO.
TPO has made major investments in technology enhanced digital and blended learning platforms that cater to, and keep pace with, the modern styles of learning, providing graduates with an immersive learning experience.
TPO provides consultancy services to clients including vessel operators and the owners offshore assets.
Before the Petition could be heard on the merits however, Roland already filed with the Court of Appeals (CA), a petition for certiorari with a prayer for the issuance of a writ of preliminary injunction assailing the TPO mainly because it violates the due process clause of Constitution.
The pathognomonic feature that differentiates TPO from other disorders affecting the airways, such as amyloidosis, is the intact posterior wall of the trachea in TPO (3, 4).
To achieve the lowest TPO, the first point to check is dissolved oxygen concentration in wine before the start of bottling.
Global Banking News-June 29, 2017--Home Point Financial announces TPO channel expansion
The Trade Promotion Organization of Iran (TPO) is to send a trade, marketing and investing delegation to Russia from September 15 to 18 to explore avenues of exporting Iranian products to the country, the official website of TPO announced.
Thrombopoietin (TPO) is a key regulator of megakaryopoiesis and megakaryocyte progenitor proliferation by promoting stem cell differentiation into megakaryocytes and their expansion, hence, boosting platelet production [9, 10].
Adopted as a replacement for more traditional materials like metal, thermplastic polyolefins (TPOs) are said to help deliver improved fuel economy and the protection of important car features, along with premium and durable interior and exterior aesthetics.