Also found in: Dictionary, Thesaurus, Legal, Financial, Acronyms, Encyclopedia, Wikipedia.
Related to TPHA: bilharziasis, RPR


determination of the purity of a substance or the amount of any particular constituent of a mixture.
biological assay bioassay; determination of the potency of a drug or other substance by comparing the effects it has on animals with those of a reference standard.
CH50 assay a test of total complement activity as the capacity of serum to lyse a standard preparation of sheep red blood cells coated with antisheep erythrocyte antibody. The reciprocal of the dilution of serum that lyses 50 per cent of the erythrocytes is the whole complement titer in CH50 units per milliliter of serum.
enzyme-linked immunosorbent assay (ELISA) any enzyme immunoassay using an enzyme-labeled immunoreactant (antigen or antibody) and an immunoadsorbent (antigen or antibody bound to a solid support). A variety of methods are used for measuring the unknown concentration, such as either competitive binding between the labeled reactant and unlabeled unknown or a sandwich technique in which the unknown antigen binds both the immunoadsorbent and labeled antibody. One of the uses of ELISA is to screen blood for antibody to the human immunodeficiency virus; a positive result indicates probable exposure to the virus and possibly that the virus is in the blood. Since false-positives can occur, a back-up test is used to confirm positive findings.
 ELISA: With antigen capture ELISA, the wells are coated with antibody to the virus. The sample containing virus (1) is added and, after washing several times, enzyme conjugated to an antibody to the virus is added (2). Finally, after a further cycle of washing, the enzyme's substrate (3) is added. A colored product is formed if the viral antigen is present in the sample (4). From Hart and Shears, 1997.
microhemagglutination assay–Treponema pallidum (MHA-TP) a Treponema pallidum hemagglutination assay using microtechniques; used in the detection of syphilis.
radioreceptor assay a radioligand assay in which a radiolabeled hormone is used to measure the concentration of specific cellular receptors for the hormone in tissue specimens, an example being radioassay of estrogen receptors in breast tissue.
thyroid-stimulating hormone assay thyroid-stimulating hormone test.
Treponema pallidum hemagglutination assay (TPHA) a treponemal antigen serologic test for syphilis using tanned sheep red blood cells coated with antigen from the Nichol's strain of Treponema pallidum and treated patient serum; it is similar in sensitivity and specificity to the FTA-ABS test. This test is not useful for individuals who have had syphilis in the past.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
Table 1 shows comparison of CLIA with RPR and TPHA. The performance of CLIA with TPHA is shown in table 2.
Moreover, the agreement between DIALAB-ELISA and TPHA was nearly perfect (kappa value 0.96) as compared to that of ECOTEST-RPR and Randox-TPHA (kappa value of 0.88).
But take a country like Tanzania: TPHA could be engaging in fundraising, collective anti-poaching and major information sharing with the scientific community.
Guidelines from the United States of America (USA) and Europe recommend a combination of two tests: the first one is a non treponemal (cardiolipin, reaginic) test, essentially Venereal Disease Research Laboratory (VDRL) or rapid plasma reagin (RPR); and the second is a treponemal test, essentially TP haemagglutination assay (TPHA), TP particle agglutination, or the fluorescent treponemal antibody absorption (FTA-abs) test (3,4).
Hastaligin okuler bulgularinin herhangi bir evrede gorulebilmesi hatta kimi olgularda ilk bulgu olarak gorulmesi ve bir cok farkli hastaliga benzer klinik tablo olusturmasi nedeniyle sifilizi dusundurecek diger bulgular olmasa dahi okuler inflamatuvar olgularda VDRL ve rapid plasma reagin gibi tarama testlerinden faydalanarak, bunlarin pozitif olmasi halinde ise floresan treponemal antikor absorbsiyon testi ve TPHA testleri ile taniyi dogrulayarak hastaligin evresine gore uygun tedavinin baslanmasi saglanabilir.
The syphilis serologic testing for each sample was performed using a RPR test with antigens containing cardiolipin, lecithin, and cholesterol (bioMerieux, Netherlands), a TPHA test with antigens of the Nichols strain of T.
We need to respect the preliminary screening tests (after the European guideline for the management of syphilis): TPHA, MHA-TP or TPPA are the best single screening tests.
As provas sorologicas sao as mais utilizadas no diagnostico da sifilis e dividem-se em: testes nao treponemicos, que sao utilizados no diagnostico e seguimento pos-tratamento, dos quais fazem parte o VDRL (Venereal disease research laboratory) e o RPR (Rapid plasma reagin), e os testes treponemicos, validos para confirmacao da infeccao, que incluem o FTA-ABS (Fluorescent treponemal antibody absorption) e TPHA (Treponema pallidum hemagglutination assay).
Bronzan et al., Nurses: 68.2% Nurses: on- 100% found on- 2007 [17] preferred on/ site testing site ICS test site ICS over was acceptable easy to on/site RPR and and favoured perform, fast, off/site RPP/ over off-site and reliable, TPHA. testing as it compared to 95% allowed for who found on- prompt site RPR time diagnosis, consuming, patient unreliable, and education, and difficult to immediate perform and treatment.
He, with the other members, restructured TPHA to fit with the new health care environment, opening windows for rural and smaller hospitals.
The Drive for 12 in '13 is an effort to exceed 1,200 TPHA members by Sept.