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Related to TNPO1: TRPV1
TNPO1A gene on chromosome 5q13.2 that encodes a beta subunit of the karyopherin receptor complex, which interacts with nuclear localisation signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit, which recognises the nuclear localisation signal, and a beta subunit, which docks the complex at nucleoporins.
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