TNK-tPA

TNK-tPA

Cardiology A proprietary bioengineered agent administered as an IV bolus, which dissolves coronary clots without interfering with other clotting factors. See ASSENT I, Bolus thrombolytic.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Tenecteplase (TNK-tPA) is a mutant form of t-PA that has a longer half-life.
Human gene for tPA was modified by genetic engineering where different amino acids occur at three locations to yield tencepteplase (TNK-tPA).
ENTIRE (ENoxaparin and TNK-tPA with or without GP IIb/IIIa Inhibitor as REperfusion strategy in ST elevation MI), also referred to as TIMI 23, will examine TIMI flows through coronary angiography, utilizing varying dosing regimens of TNKase(TM) (Tenecteplase), the low-molecular-weight heparin Lovenox, the anti-platelet agent ReoPro, and heparin sodium.