TIMI risk score

TIMI risk score

abbreviation for thrombolysis in myocardial infarction risk score. A simple integer score for bedside risk stratification of patients with acute myocardial infarction (MI). Point values are assigned to each of a set of independent prognostic variables (e.g., age, diabetes mellitus, history of hypertension, history of angina, ST segment elevation), and the sum of points is the score. Several studies have validated the score as a measure of risk of all-cause mortality and recurrent MI; predictors have varied slightly between studies.
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2) is an ADP that combines a TIMI risk score of 0, a nonischemic EKG, and negative serial troponin measures at 0 and 2 h to identify patients at low risk for MACE at 30 days.
He also talked about TIMI Risk Score. Some patients whoa are already on Aspirin therapy but still have ACS, they are known as non-responders.
Also, obese patients tended to present with NSTEMIs having lower-risk features, as reflected in their TIMI risk scores. The prevalence of a high TIMI risk score was only 28.5% in obese patients, compared with 35.4% in overweight and 51.4% in lean patients.
Adjusted analyses incorporated clinical elements of the TIMI risk score for unstable angina/NSTEMI, including age, recent aspirin use, multiple coronary risk factors, known coronary disease, and ST-segment deviation (18).
We used a multivariable Coxproportionalhazards regression model to adjust for (a) TIMI risk score covariates, as defined by age > 65 years, known coronary arterydisease, diabetes, hypertension, dyslipidemia, severe angina ([greater than or equal to] 2 episodes in 24h), ST changes [greater than or equal to]0.5 mm, and aspirin use; (b) other characteristics of interest: smoking, history of HF, creatinine clearance <60 mL/min (as defined by the Cockcroft-Gault equation); and (c) other biomarkers, including cTnI, BNP, myeloperoxidase (MPO), and high-sensitivity C-reactive protein (hsCRP).
Risk scoring and prognostication by means of the TIMI risk score (23) (Table 1) for unstable angina or non-ST elevation myocardial infarction has recently been introduced and is widely implemented.
Patients with cardiac troponin results above cutoff by either of the 2 assays were significantly older; had more cardiovascular risk factors, more often a history of atherosclerotic diseases or events, and a higher TIMI risk score; and more frequently received aspirin, [beta]-blockers, and other medical treatments.
The highest risk patients (recent MI, multivessel CAD, PAD, and highest TIMI risk score) have the greatest benefit.
The TIMI risk score for unstable angina/non-STelevation MI: A method for prognostication and therapeutic decision making.