LOFT and the
TIMI study group analysis were sponsored by Merck.
Coronary flow as measured by
TIMI flow grade was similar among the three groups.
All patients were divided into two groups based on the post-procedural
TIMI flow in the IRA:
TIMI flow [?
La referencia de los trabajos previos y la participacion en las guias de practica clinica de sindrome coronario agudo del Ministerio de Salud y Proteccion Social esta relacionada con el hecho del desarrollo de una pregunta con la estrategia PECOT, con respecto a la recomendacion de la utilizacion de la escala
TIMI o GRACE en este escenario, que aunque no genero directamente la idea de investigacion, le dio mayor importancia dado el vacio existente.
Esto hace llegar a la conclusion que el modelo basado en la escala de
TIMI no es adecuado para la clasificacion de los pacientes en rangos de probabilidad pretest.
Because acute ischemic heart disease usually causes more marked increases in serial values, not many men or women are misclassified as in the study reported by the
TIMI group.
TIMI score and GRACE score were categorised and correlated with angiographic findings by logistic regression.
Among the patients enrolled in the study, the greatest
TIMI frame count was observed in group 1c.
After RT we also observed no flow in the target vessel and these patients had improvement of
TIMI flow with intracoronary vasodilators.
We are very pleased that the
TIMI Study Group will be carrying out the Phase II evaluation of BB-10153 and look forward to working closely with the group and to receiving the benefit of their outstanding experience in this area.
The primary endpoint was clinically significant bleeding (composite of
TIMI major bleeding,
TIMI minor bleeding or bleeding requiring medical attention).
