MYOC

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MYOC

A gene on chromosome 1q23-q24 that encodes myocilin, a protein thought to play a role in cytoskeletal function, which is highly expressed in ocular tissues including the trabecular meshwork, which regulates intraocular pressure.

Molecular pathology
MYOC mutations cause hereditary juvenile-onset open-angle glaucoma.
References in periodicals archive ?
The I[sub]p/I[sub]0, AIR[sub]0′~10′, and AUC[sub]ins-IVGTT values of the TDM group were higher than those of the T2DM group but were lower than those of the TNGT, TIGR, NGT, and IGR groups.
In addition, as compared with the IGR group, the HOMA-[sz] value of the TIGR group was increased.
TIGR also gives battalions the tools to oversee events occurring within their subordinate companies and provide those units with instant feedback.
In this way, TIGR has streamlined information dissemination, which greatly enhances situational understanding and awareness.
TIGR had by this time sequenced the smallpox virus, but the genomes of viruses are minuscule compared to those bacteria.
A few weeks later, Venter announced that TIGR had deciphered the first genome of a living organism.
Over the last few years, Venter and his TIGR colleagues have pioneered a novel strategy to quickly sequence genomes and have proved the method effective with the sequencing of the first two bacterial genomes (SN: 6/10/95, p.
Bult of TIGR, Venter, Woese, and their colleagues in the Aug.
Probably the largest private enterprise sequencing cDNAs is TIGR (pronounced "tiger") and an associated company, Human Genome Sciences (HGS).