MYOC

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MYOC

A gene on chromosome 1q23-q24 that encodes myocilin, a protein thought to play a role in cytoskeletal function, which is highly expressed in ocular tissues including the trabecular meshwork, which regulates intraocular pressure.

Molecular pathology
MYOC mutations cause hereditary juvenile-onset open-angle glaucoma.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
The ratios of peak values, declines, and delayed peaks for the TNGT, TIGR, and TDM groups were 6.3%, 11.4%, and 55.9%, respectively, while the ratios for the NGT, IGR, and T2DM groups were 9.1%, 32.1%, and 80.0%, respectively.
Being able to see the battlefield using the TIGR software was "really awesome," said Maxon.
Companies using TIGR can store data in a common database, which enables easier analysis, collaboration, and information-sharing.
Bjorck is the Principle Investigator for the first clinical study of the TIGR Matrix Surgical Mesh that recently completed enrollment.
Strausberg began his career at JCVI in 2003 as vice president for research at TIGR after leaving the NIH's National Cancer Institute.
Laptop computers to run TIGR and Palantir; associated servers so that the information is available to any unit in the SBCF.
With the help of TIGR scientists, ARS researchers are working to assign genes to these various sequences.
The rice genome promises to inspire new cereal crop research," says TIGR President Claire Fraser.
In the glaucoma area, the company has continued to focus genomic research on the TIGR gene, among other genes in its genomic portfolio.
Shortly after the identification of the first candidate gene for primary open angle glaucoma, the "trabecular meshwork inducible gluco-corticoid response" (TIGR) gene, the gene Myocilin (MYOC), was isolated from cDNA from human retina (Stone et al.