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transfer factor

a factor occurring in sensitized lymphocytes that has the capacity to transfer delayed hypersensitivity to a normal (nonreactive) individual. It confers cell-mediated immunity and therefore has been found to be useful in treating conditions in which there is a disorder of immune response. As an adjunct to antibiotic therapy it is useful in the treatment of such antibiotic-resistant diseases as candidiasis, coccidioidomycosis, and leprosy.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

T gene

A genes on chromosome 6q27 that encodes brachyury, an embryonic nuclear transcription factor that effects transcription of genes required for mesoderm formation and differentiation, and mediates epithelial-mesenchymal transition. It is localised to notochord-derived cells.

Molecular pathology
Brachyury is the definitive diagnostic marker of chordoma; it is overexpressed in various cancers and promotes invasion.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Abbreviation for tuning fork.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012