TERF1

TERF1

A gene on chromosome 8q21.11 that encodes a protein which is an integral component of the telomere nucleoprotein complex. It is present at telomeres throughout the cell cycle and inhibits telomerase, acting in cis to limit elongation of chromosome termini.
Mentioned in ?
References in periodicals archive ?
7] Human genes: DKC1, dyskeratosis congenita 1, dyskerin; TINF2, TERF1 (TRF1)-interacting nuclear factor 2; TERC, telomerase RNA component; TERT, telomerase reverse transcriptase; NHP2, NHP2 ribonucleoprotein homolog (yeast); NOP10, NOP10 ribonucleoprotein homolog (yeast); WRAP53 (formerly TCAB1), WD repeat containing, antisense to TP53; CTC1, CTS telomere maintenance complex component 1.