thyroid dyshormonogenesis 2A
(redirected from TDH2A)thyroid dyshormonogenesis 2A
An endocrinopathy (OMIM:274500) caused by defective conversion of iodide to organically bound iodine (organification), which can be partial or complete.Molecular pathology
Defects of TPO, which encodes a membrane-bound glycoprotein enzyme that iodinates tyrosine residues in thyroglobulin, cause thyroid dyshormonogenesis 2A.