TFAM

(redirected from TCF6)

TFAM

A gene on chromosome 10q21 that encodes a transcription factor which activates mitochondrial transcription and participates in mitochondrial genome replication. TFAM is required for regulating mitochondrial genome copy number and for embryonic development.

Molecular pathology
Targeted disruption of TFAM expression in mice results in physiological model of Kearns-Sayre syndrome.
References in periodicals archive ?
NORTH FIELD GAS/CONDENSATE OUTPUT & LNG VENTURES 1991-2005/7 Gas Condensate/Dedicated LNG Start-Up MCF/DayNGL (b/d) Reserve Capacity Sept 1991, Phase-1* 880 40,000 7 TCF -- 1997/98 Qatargas* 1,100 50,000 10 TCF 6M t/y 1999-2000 Rasgas-1* 1,100 50,000 10 TCF6.6M t/y 2002/04 Rasgas-2* 1,100 50,000 10 TCF6.6M t/y 2004 Mobil/Dolphin 1,000 48,000 8 TCFP/L Gas 2003/05 Arco* 800 38,000 6 TCFP/L Gas 2003/05 QGPC/Exxon* 1,000 NA 8 TCFSynth.