TCF7

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TCF7

A gene on chromosome 5q31.1 that encodes a transcription activator involved in T-cell differentiation, which is required for survival of immature CD4 and CD8 thymocytes.
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Table 5 Current estimate (IPCA coupon) of theoretical cash flows Current estimate (R$ million) TCF1 TCF2 TCF3 TCF4 Reference date 1 - 06/29/2012 756.7 520.8 623.5 737.1 Reference date 2 - 12/29/2011 719.4 458.7 570.8 711.5 Reference date 3 - 06/30/2011 638.3 385.2 493.6 644.5 Range 118.4 135.6 129.9 92.6 Source: Prepared by the authors.
Jannot et al (31) reported the heterozygous germline-inactivating mutations of the CYP1B1 gene might increase the incidence of HA in women with TCF1 (HNF1A) gene mutations.
(d) Relative gene expressions of Hif1[alpha], Tcf1, Lef1, Tcf3, Tcf4, Axin2, and NeuroD1 detected in 2-day-old EBs derived from wild-type (white bars) and Hif1[alpha]-deficient cells (black bars) by real-time quantitative PCR analysis.
Maturity-onset diabetes of the young (MODY) Tipe Mutation How common MODY 1 HNF4A Hepatocyte Rare nuclear factor 4 [alpha] MODY 2 GCK Glucokinase MODY 2 is the second-most common form of MODY MODY 3 TCF1 Hepatic nuclear Rare factor 1 [alpha] or HNF1 [alpha] or HNF1A MODY 3 is the most common form of MODY.
Murine Mtgr1 associates with Tcf4 and Tcf1 in vitro and can repress the expression of a Tcf4-dependent reporter gene.
Hoffman et al., "Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal," Nature Cell Biology, vol.