TCF7

(redirected from TCF1)
Also found in: Acronyms.

TCF7

A gene on chromosome 5q31.1 that encodes a transcription activator involved in T-cell differentiation, which is required for survival of immature CD4 and CD8 thymocytes.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Jannot et al (31) reported the heterozygous germline-inactivating mutations of the CYP1B1 gene might increase the incidence of HA in women with TCF1 (HNF1A) gene mutations.
(d) Relative gene expressions of Hif1[alpha], Tcf1, Lef1, Tcf3, Tcf4, Axin2, and NeuroD1 detected in 2-day-old EBs derived from wild-type (white bars) and Hif1[alpha]-deficient cells (black bars) by real-time quantitative PCR analysis.
Murine Mtgr1 associates with Tcf4 and Tcf1 in vitro and can repress the expression of a Tcf4-dependent reporter gene.
Hoffman et al., "Opposing effects of Tcf3 and Tcf1 control Wnt stimulation of embryonic stem cell self-renewal," Nature Cell Biology, vol.