TBX2

TBX2

A gene on chromosome 17q23 that encodes a DNA-binding member of the phylogenetically conserved family of genes that have a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in regulating development. Gene expression studies suggest that TBX2 may play a role in immortalising tumours.
References in periodicals archive ?
Putative oncogenes at 17q23 that are upregulated in the ACC dataset queried using Oncomine 3 (45) include TBX2 and PPM1D.
TBX2 and TBX4 are members of a closely related gene family, the T-box genes, that is involved in development.