TATA box


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Related to TATA box: CAAT box

TATA box

a highly conserved bacterial DNA sequence found about 25 bp upstream from the transcription start site of genes, usually flanked by GC-rich sequences; binding site of transcription factors but not RNA polymerase.

TATA box

or

Hogness box

a short CONSENSUS SEQUENCE generally to be found in the PROMOTOR in EUKARYOTES. The sequence consists of seven or eight NUCLEOTIDES: 5′-TATA(A/T)A(A/T)-3′. It is located about 25 to 30 base pairs UPSTREAM of the start of the TRANSCRIPTION site and serves as a binding site for RNA POLYMERASE. It is similar to the PRIBNOW BOX in PROKARYOTES.

TATA box

a eukaryotic DNA sequence usually TATAAATA, similar to the Pribnow box of Escherichia coli, occurring in the promoter region 25 to 35 bases upstream from the transcriptional start site that binds the general transcription factor TFIID which begins the formation of the transcription initiation complex which includes RNA polymerase.
References in periodicals archive ?
A typical TATA box was present at -32 and potential sites of C/EBPp (CCAAT/Enhancer-Binding Protein [beta]) are present at -1,846 and -2,110 (data not shown).
Hoechst 33342 induces apoptosis, inhibitstopoisomerase I and alters TATA box binding protein/DNA complexes in HT-144 melanoma cells.
PCR primers were designed from the GenBank reference sequence for UGT1A1 to amplify a small (59-bp) amplicon containing the UGT1A1 promoter TATA box.
This region includes the TATA box, the NF-1 binding site, and three of the eight AhR response elements (1,16,18,19).