TAS2R4(redirected from T2R4)
TAS2R4A gene on chromosome 7q31.3-q32 that encodes a gustducin-coupled taste receptor implicated in the perception of bitter compounds in the oral cavity and GI tract. In airway epithelial cells, binding of denatonium increases intracellular calcium ion concentration and stimulates ciliary beat frequency.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.