T cell

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Related to T-lymphocytes: thymus gland, B-lymphocytes

T lym·pho·cyte

a lymphocyte formed in the bone marrow from which it migrates to the thymic cortex to become an immunologically competent cell; T lymphocytes have long lifespans (months to years) and are responsible for cell-mediated immunity; T lymphocytes form rosettes with sheep erythrocytes and differentiate and divide in the presence of transforming agents (mitogens); T lymphocytes have characteristic T cell receptor-CD3 complexes as surface markers and may be further categorized by function, such as helper and cytotoxic.
See also: B lymphocyte.
Synonym(s): T cell
Farlex Partner Medical Dictionary © Farlex 2012

T cell

Any of the lymphocytes that mature in the thymus and have the ability to recognize specific peptide antigens through the receptors on their cell surface. Also called T lymphocyte.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

T cell

A specialised myocyte found in clusters in the sinus node, which is intermediate in size, structure, and organisation between P cells and normal atrial myocytes, and connect swith either of these cells; perinodal T cells surround the sinus tract and are thought to “bundle” impulses leaving the sinus node and to filter premature ectopic atrial impulses.

A thymus-derived white cell responsible for cell-mediated immunity and immunoregulation which is the most complex cell of the immune system, given:
(1) The diversity of T-cell types, including T cells with activator, cytotoxic, delayed hypersensitivity and suppressor activities;
(2) The wide range of cytokines, growth factors and immune modulators produced by activated T cells;
(3) The complexity of T-cell interaction with exogenous and endogenous antigens (e.g., mediation of delayed hypersensitivity, graft-versus-host disease);
(4) The complexity of T-cell maturation in the thymus.

50 to 70% of circulating WBCs are granulocytes (neutrophils); the rest are lymphocytes, of which T cells (defined as having “pan T cell” markers), CD2 and CD7 and other T-cell markers (e.g., CD1, CD3, and CD5) comprise 70 to 85%; B cells comprise 15 to 30%.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

T lym·pho·cyte

A thymocyte-derived lymphocyte of immunologic importance that is responsible for cell-mediated immunity. These cells have the characteristic T3 surface marker and may be further divided into subsets according to function, such as helper, suppressor, and cytotoxic.
See also: B lymphocyte
Synonym(s): T cell.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

T cell

One of the two broad categories of LYMPHOCYTE, the other being the B cell group. Subsets of T cells with different functions include cytotoxic T cells (CD8+ T cells) which destroy tumour cells and cells infected with viruses; helper T cells (CD4+ T cells) which assist the immune response, and are a target of HIV infection; REGULATORY T CELLS, formerly called suppressor T cells, which are essential for the maintenance of immunological tolerance; and natural Killer T cells (NKT cells).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

T cell

A type of white blood cell produced in the thymus gland that regulates the immune system's response to diseased or malignant cells. It is possible that a subcategory of T cells known as CD4 cells plays a role in Ménière's disease.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

T lym·pho·cyte

Lymphocyte formed in bone marrow from which it migrates to thymic cortex to become an immunologically competent cell.
Medical Dictionary for the Dental Professions © Farlex 2012

Patient discussion about T cell

Q. How are cancer cells similar to normal cells, and how are they different? I know that a similarity would be cells regenerate, and a difference would be cancer cells grow uncontrollably. Is there anything else?

A. I learned a lot of new things from the answers. Thanks.

Q. what is difference between normal cell and a cell infected with cancer?

A. Malignant cells (cancerous cells, which is the correct term, since cancer isn't transmitted from cell to cell like microbes), are immortalized cells: the life span of each cell in our body is tightly regulated according to the body's needs, so cells don't multiply endlessly and eventually undergo programmed death (called apoptosis). Cancerous cells succeed to overcome this regulation, and therefore become immortalized: either excessive multiplication or avoidance of death.

You may read more here:

Q. What tests can the doctors do to see if I have cancer cells still in me? Am using my friend user name. I had a mastectomy in October of the 3cms lump. They also removed lymph nodes from armpit. They found that 2 nodes were slightly infected and 2 blood vessels leading away were the same. My oncologist says I should start chemo for 5 months followed by 5 wks of radiotherapy. I am awaiting the results from bone, heart, lungs and blood tests. What tests can the doctors do to see if I have cancer cells still in me?

A. You need to have your own self examination, which you can get guidance from doctor and all the tests which you already had and the tests which you are awaiting. Like you may have clinical examination, mammograms- which you already had, breast biopsy, ultrasonography, post biopsy pathology test, HER-2 gene test to find the speed of your tumor growth. Tests to check cancer spread – like lymph, bone, liver and lungs whose results you are waiting for.

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References in periodicals archive ?
Changes in Ca 2+, calcineurin, and nuclear factor of activated T cell in T-lymphocytes following changes in mitofusin-2expression
[CD4.sup.+] and [CD8.sup.+] T-lymphocytes located in nonmucosal lymph nodes get activated, migrate to the intestinal wall, and transiently accumulate in the intraepithelial compartment [17, 18].
Postmortal examination of an enlarged lymph node showed typical features of AITL, including effacement of nodal architecture with "burn out" lymphoid follicles (pattern II), proliferation of arborizing high endothelial venules, and the infiltration of CD4-positive atypical small T-lymphocytes with TFH phenotype [7].
After obtaining preliminary plasma RANTES concentrations, four time points (before induction, before CPB, at 2 and 4 h after beginning CPB) were selected to isolate T-lymphocytes from whole blood for analyzing intracellular microRNA-125a expression by quantitative real-time reverse transcription polymerase chain reaction (qRT-PCR).
Declining CD4+ T-lymphocyte counts are associated with increased risk of enteric parasitosis and chronic diarrhea: results of a 3-year longitudinal study.
There are data on the possibility of the involvement of the DNase activity of T-lymphocytes not only in the DNA fragmentation induced by cytotoxic T lymphocytes (CTL) to target cells, but also in the process of programmed death of type 1 of these cytotoxic cells (CTL).
The T-lymphocytes and hemoglobin of experimental rabbits were significantly improved by the provision of zinc fortified apricots with maximum T-lymphocytes and hemoglobin were observed in G3 (apricot containing 2% chitosan coating with 50 ppm ZnSO4) 22.341.29 and 13.070.53 % followed by G1 (apricot containing 2% alginate coating with 50 ppm ZnSO4) G4 (apricot containing 2% chitosan coating with 50 ppm ZnCl2) and G2 (apricot containing 2% alginate coating with 50 ppm ZnCl2) as 22.211.35 and 12.940.47, 22.021.14 and 12.780.45 and 21.501.14 and 12.610.51 % as comparison to G0 by 21.221.13 and 12.320.36 %, respectively.
These new findings suggest that white blood cells called T-lymphocytes are responsible for a signifi-cant part of the heart damage, as they can become activated during a heart attack and travel into the heart muscle.
These new findings suggest that white blood cells called T-lymphocytes are responsible for a significant part of the heart damage, as they can become activated during a heart attack and travel into the heart muscle.
KEY WORDS: Antioxidant; Mercuric chloride; T-lymphocytes; B-lymphocytes; Pollutants; Lipid peroxidation.
This phenomenon is related in part to the production of interlukin-10 by peripheral blood T-lymphocytes during active tuberculosis [15].