9) Cyclosporine and tacrolimus have inhibitory effects on T-helper lymphocyte
production of IL-2, IL-2 receptors (IL-2r), and interferon gamma (IFN-[gamma]) as well as to a lesser degree on the production of other cytokines (IL-3, 4 and 5, TNF-[alpha] and [beta]) that lead to altered T-lymphocyte and B-lymphocyte function.
Sources of variability in repeated T-helper lymphocyte
counts from human immunodeficiency virus type 1-infected patients: total lymphocyte count fluctuations and diurnal cycle are important.
Interleukin-9 (IL-9) is an attractive therapeutic target because the multifunctional cytokine has been shown in experimental models to increase airway inflammation, airway obstruction, airway hyperresponsiveness, mucin production, mast cell generation, and T-helper lymphocyte
type 2 (Th2 lymphocyte) and eosinophil accumulation, explained Dr.
This disease results from an exaggerated cellular immune response (acquired, inherited, or both) to a limited class of persistent antigens or self-antigens and to an exaggerated T-helper lymphocyte
HIV is cytotoxic to T-helper lymphocytes
, which in turn leads to dysregulation of B cells and altered release of cytokines.
Emphasis on cell-mediated immunity versus humoral immunity changes according to the type of T-helper lymphocytes
responding to an infectious threat.
Heterosexual transmission of human immunodeficiency virus: association with severe depletion of T-helper lymphocytes
in men with hemophilia.
Spurred by an underactivation of the T-helper lymphocytes
that promote inflammatory cellular immunity (Th1) and an overactivation of those that promote antibody and allergic response (Th2), a relatively overactivated Th2 system contributes to the pathophysiology of schizophrenia, said Dr.
This new drug works by interfering with the binding of HIV-1 envelope glycoprotein gp120 to its CD4 cellular receptor that is expressed primarily on the surface of t-helper lymphocytes
Frequency and phenotype of human T-helper lymphocytes
that can react to allogeneic endothelial cells.