T-helper cells

T-help·er cells (Th),

a subset of lymphocytes that secrete various cytokines that regulate the immune response: subset 1, which synthesize gamma-interferon and TNF-β and are involved in cell-mediated immunity; subset 2, which synthesize IL-4, IL-5, and IL-9 and are involved in immunoglobulin synthesis.
Synonym(s): helper cells

T-help·er cells

(Th) (hel'pĕr selz)
A subset of lymphocytes that secrete various cytokines that regulate the immune response.
Synonym(s): helper cells.

T-helper cells

A cellular component of the immune system that plays a major role in ridding the body of bacteria and viruses, characterized by the presence of the CD4 protein on its surface; the type of cell that divides uncontrollable with CTCL.
References in periodicals archive ?
Antigen Express scientists, and others, have shown clearly that suppression of expression of the Ii protein in cancer cells allows for potent stimulation of T-helper cells and prevents the further growth of cancer cells.
Another major role that they perform is the activation of T-helper cells and cytotoxic T-lymphocytes which are mainly responsible for elimination of cancerous cells.
T-helper cells identify and tag invaders for elimination by the immune system.
The immunohistolochemical methods reveal that the number of T-helper cells was 6,48 [+ or -] 1,94 (1 [mm.
Results: Cell numbers, percentage of CD25 expressing T-helper cells and levels of IL-6 and TNF-[alpha], but not of IL-10 were significantly elevated after combined treatment of PBMC with PHA and VALE or OA, respectively.
The Mayo Clinic research in mice showed that Antigen Express technology that activated T-helper cells did not activate T regulatory cells, or immune suppressor cells, Generex said yesterday in a news release.
The paper describes a study on activation of innate immune cells and T-helper cells in normal and athymic BALB/c mice by three mushroom sclerotial polysaccharides.
Activated T-helper cells are essential in determining antibody class switching, in the activation and growth of cytotoxic T cells, and in maximizing bactericidal activity of phagocytes such as macrophages.
The researchers discovered that heightened Th2 (the hormonal messengers of T-helper cells that produce an allergic response) reactivity in the ABPA group correlated with a lower average blood level of vitamin D.
ORAC has shown significant correlation to markers such as C-reactive protein, serum lipid levels, T-helper cells, Interleukin 1a and other markers, which are implicated in such critical pathways.
Individuals who carry the T allele in -590C/T polymorphism of the interleukin 4 (IL4) gene (rs2243250) have a higher proportion of IL-4-producing T-helper cells (4).
For many years scientists have understood that after HIV gets into someone's body, it starts infecting lots of T-helper cells.