T-helper cell


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Related to T-helper cell: Effector T cells, T cytotoxic cells

T-helper cell

(tē′hĕl′pər)

T-helper cell

A type of cell that recognizes foreign antigens and activates T- and B-cells in an immune response.
References in periodicals archive ?
Second, PPIA 6850G was associated with upregulated T-helper cell activation ([CD25.sup.High] [CD4.sup.+] and [CD3.sup.+] T cells) in NS conditions, accounting for 86% of the interpatient variability, which was not previously evidenced in healthy volunteers (8).
In order to test the effects of fruit juice on T-helper cell phenotype, we quantified the concentrations of T-cell differentiation cytokines (IL-2, IL-4, IL10, and IFN-[gamma]) in the animal plasma, using Abcam Rat ELISA kit for IL-2, IL-4, and IL-10 (Abcam, Cambridge, USA) and Bio-Legend Rat LEGEND MAX[TM] ELISA kit for IFN-[gamma] (Bio-Legend, San Diego, CA, USA).
T-helper cells identify and tag invaders for elimination by the immune system.
Intact T-helper cell memory function is required for effective reactivation and stimulation of cytotoxic CD8+ T-cells.
To date, numerous T-helper cell subsets have been defined mainly based on the expression of master transcriptional regulators and cytokine production profiles (Figure 2) [7].
As tuberculous disease is initiated and advances in the body, there appears to be a shift from a T-helper cell type 1 (TH1) protective response to a T-helper cell type 2 (TH2) pathway which is less effective and more injurious to tissue.
Type I T-helper cell predominance and interleukin-12 expression in the gut of patients with Crohn's disease.
TFN-[alpha] is involved in maintaining a T-helper cell type 1 immune response because it induces production of interleukin-12 (IL- 12) and IL- 18, with subsequent production of fungicidal interferon-[gamma] (8).
A growing data set suggests that pre- and probiotic supplementation in infancy can enhance IgA responses to antigenic challenge, and favorably influence T-helper cell balance, thus reducing inflammatory and/or allergic responses.
Clear psoriasis faster than conventional phototherapy, and may become predominant in the future CNTO-1275 Anti-interleukin-12 antibody that switches the immune response from a T-helper cell 1 cytokine reaction most commonly seen in psoriasis to a T-helper cell 2 cytokine response T-cell receptor vaccines Have been developed and are undergoing clinical trials in patients with psoriasis Pimecrolimus Used orally.
Humphreys presented: "Transmucosal Delivery of Therapeutics by RapidMist(R) Technology and TH-1 T-helper cell Ii-Key/MHC Class II Peptide Vaccines against Cancer and HIV."
Waiting until the chronic phase of infection to initiate potent antiretroviral therapy does not lead to restoration of T-helper cell function.