T-cell lymphoma


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T-cell lymphoma

A malignant proliferation of T cells arising in the skin, diagnosed by detecting rearrangement of the T-cell receptor's β chain; TCLs are often 'driven' by EBV and other viral infections; 90% of all Pts with TCL have extracutaneous involvement when diagnosed. See Mycosis fungoides.
T-cell lymphomas
Small lymphocytic (well-differentiated lymphocyte-like) lymphoma–13%
Convoluted cell lymphoma or poorly-differentiated lymphocytic lymphoma–52%
Immunoblastic sarcoma or 'histiocytic' lymphoma–19%
Mycosis fungoides/Sézary syndrome–11%
Lymphoepithelial cell (Lennert's) lymphoma–5%
Cutaneous T-cell lymphoma
HTLV (I, II)–induced lymphoma
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

T-cell lymphoma

See MYCOSIS FUNGOIDES.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
Gemmill, "Cutaneous T-cell lymphoma," Seminars in Oncology Nursing, vol.
Type II enteropathy-associated T-cell lymphoma is a subset of EATL which does not appear to be associated with celiac disease and therefore has a broader geographic distribution.
The 200 cases of non-Hodgkin's lymphoma included 118 T-cell lymphomas, 30 B-cell lymphomas, and 52 indeterminate types.
Many aggressive B-cell NHL seen in HIV patients, especially those with plasmacytic differentiation, often lack CD20 and exhibit aberrant T-cell antigen expression [72], These lymphomas may falsely lead to an impression of T-cell lymphoma, and could thereby skew the published data reported.
Approximately 8 years after the second sample was taken, the patient was again diagnosed and found to have angiocentric T-cell lymphoma. The CE GeneScan profiles (Fig.
Gasparro of the Yale University School of Medicine is seeking cell-surface targets for psoralen -- a treatment for psoriasis and cutaneous T-cell lymphoma -- to help explain the drug's apparent ability to stimulate an immune response against abnormally dividing skin cells.
The US Food and Drug Administration (FDA) has received a supplemental Biologics License Application from United States-based Seattle Genetics, seeking approval for its Adcetris (brentuximab vedotin) in combination with chemotherapy intended for the frontline treatment of CD30-expressing peripheral T-cell lymphoma, it was reported yesterday.
MONOMORPHIC EPITHELIOTROPIC INTESTINAL T-CELL LYMPHOMA
Peripheral T-cell lymphoma (PTCL) defines a group of rare non-Hodgkin lymphomas (NHL) characterized by an aggressive clinical course and dismal prognosis.
-- Psoriasis of all severities was linked to a 3.5-fold increase in risk of cutaneous T-cell lymphoma, and severe psoriasis upped the associated risk of Hodgkin lymphoma by about 2.5 times, in a large, longitudinal, population-based cohort study.