Also found in: Dictionary, Thesaurus, Legal, Financial, Encyclopedia.
t-plasminogen activator[plaz-min´o-jen ak´tĭ-va″tor]
see tissue plasminogen activator.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
PLATA gene on chromosome 8p12 that encodes tissue plasminogen activator, which converts inactive plasminogen to plasmin by hydrolysing a single Arg-Val bond in plasminogen, thereby playing a key role in tissue remodelling, degradation, cell migration and other cellular events. PLAT directly facilitates neuronal migration.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.