T-antigen


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T-antigen

an antigen found in cells infected by an oncogenic virus. see ONCOGENE.
References in periodicals archive ?
In addition, the RSC-like cells can coexpress CD30 (Figure, F), CD15, and PAX5, whereas CHL may have aberrant T-antigen expression and is [CD15.sup.-] in a subset of cases.
Improved detection of JC virus in AIDS patients with progressive multifocal leukoencephalopathy by T-antigen specific fluorescence energy transfer hybridization probe real-time PCR: Evidence of diverse JC virus genotypes associated with progressive multifocal leukoenceohalopathy in Southern Africa.
These experiments employed monkey COS7 cell extracts containing SV40 large T-antigen. SV40 has a different NCCR from that of JCV, but it has other palindromes that can stall forks, and its replication mechanism is similar to that of JCV.
Amino acid sequence alignments of the predicted RacPyV LT-Ag, small T-antigen (sT-Ag), viral protein (VP) 1, and VP2 were generated by using ClustalW, implemented in MEGA5 (www.
Risk factors, such as increased exposure to UV and ionizing radiation, may be involved in T-antigen mutations.
In every construct, the tag sequence included codes for the 11-aa KPPTPPPEPET epitope of simian virus 40 (SV40) large T-antigen (31,32).
Furthermore, the integrated viral genome may harbor mutations in the T-antigen coding sequence, resulting in truncation of the corresponding helicase protein (8).